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Table 2 Contrasting miliary and local hepatic TB

From: A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection

 

Miliary Hepatic TB

Local Hepatic TB

Prevalence

79%

21%

Infection origin

Lungs

Gastrointestinal system

Dissemination

Hepatic artery

Portal vein

Tubercle size

0.6-2.0 mm in diameter

>2.0 mm in diameter

Location of tubercles

Lobules of liver

Near portal triad

Clinical signs/symptoms

Cough, sputum production, hepatomegaly

Weight loss, hepatomegaly, jaundice

Diagnosis

CT scan; liver biopsy is less helpful

Liver biopsy more helpful

CT findings

Multiple, dispersed, low-density micronodules

Large, low-density nodules with calcification and peripheral enhancement

Treatment

4-drug regimen

4-drug regimen; consider drainage of abscess or surgery

  1. TB = Tuberculosis; CT = Computerized tomography.