Table 2 Antibiotic resistance profiles for isolates with serotype 23B and serotype 15A
From: Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era
Serotype 15A | Serotype 23B | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
all | MIC range | I | R | MIC 50 | MIC 90 | all | MIC range | I | R | MIC 50 | MIC 90 | |
n= | μg/ml | % | % | μg/ml | μg/ml | n= | μg/ml | % | % | μg/ml | μg/ml | |
Penicillin | 310 | 0.015 - 2 | 47.1 | 0.3 | 0.015 | 0.25 | 312 | 0.015 - 0.5 | 46.5 | 0.0 | 0.015 | 0.25 |
1992-1993 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 0 | |||||
1993-1994 | 0 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | |||||
1994-1995 | 2 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 0 | |||||
1995-1996 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 0 | |||||
1996-1997 | 0 | 0 | ||||||||||
1997-1998 | 4 | 0.015 - 0.12 | 50.0 | 0.0 | 0.015 | 0.12 | 2 | 0.015 - 0.06 | 0.0 | 0.0 | 0.015 | 0.06 |
1998-1999 | 5 | 0.015 - 0.25 | 20.0 | 0.0 | 0.015 | 0.25 | 0 | |||||
1999-2000 | 3 | 0.015 - 0.25 | 33.3 | 0.0 | 0.015 | 0.25 | 0 | |||||
2000-2001 | 3 | 0.015 - 0.12 | 33.3 | 0.0 | 0.03 | 0.12 | 0 | |||||
2001-2002 | 9 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 3 | 0.015 - 0.12 | 33.3 | 0.0 | 0.015 | 0.12 |
2002-2003 | 4 | 0.015 - 0.25 | 25.0 | 0.0 | 0.015 | 0.25 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 |
2003-2004 | 5 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 1 | 0.25 | 100.0 | 0.0 | 0.25 | 0.25 |
2004-2005 | 4 | 0.015 - 0.25 | 25.0 | 0.0 | 0.015 | 0.25 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 |
2005-2006 | 4 | 0.015 - 0.06 | 0.0 | 0.0 | 0.015 | 0.06 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 |
2006-2007 | 4 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 | 2 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 |
2007-2008 | 5 | 0.015 - 0.5 | 40.0 | 0.0 | 0.015 | 0.5 | 1 | 0.015 | 0.0 | 0.0 | 0.015 | 0.015 |
2008-2009 | 11 | 0.015 - 0.5 | 45.5 | 0.0 | 0.015 | 0.5 | 11 | 0.015 - 0.5 | 45.5 | 0.0 | 0.015 | 0.25 |
2009-2010 | 19 | 0.015 - 1 | 47.4 | 0.0 | 0.03 | 0.5 | 22 | 0.015 - 0.5 | 59.1 | 0.0 | 0.12 | 0.25 |
2010-2011 | 32 | 0.015 - 0.5 | 56.3 | 0.0 | 0.25 | 0.25 | 41 | 0.015 - 0.5 | 39.0 | 0.0 | 0.015 | 0.25 |
2011-2012 | 51 | 0.015 - 0.5 | 52.9 | 0.0 | 0.12 | 0.25 | 72 | 0.015 - 0.25 | 44.4 | 0.0 | 0.06 | 0.25 |
2012-2013 | 67 | 0.015 - 1 | 61.2 | 0.0 | 0.25 | 0.25 | 73 | 0.015 - 0.5 | 52.1 | 0.0 | 0.12 | 0.25 |
2013-2014 | 76 | 0.015 - 2 | 50.0 | 1.3 | 0.25 | 0.25 | 80 | 0.015 - 0.5 | 48.8 | 0.0 | 0.015 | 0.25 |
Cefotaxime | 310 | 0.015 - 1 | 0.0 | 0.0 | 0.015 | 0.12 | 312 | 0.015 - 0.5 | 0.0 | 0.0 | 0.03 | 0.06 |
Erythromycin | 310 | 0.06 - 256 | 0.3 | 48.7 | 0.12 | 256 | 312 | 0.06 - 256 | 0.0 | 2.9 | 0.12 | 0.12 |
Clindamycin | 310 | 0.06 - 256 | 0.6 | 46.5 | 0.12 | 128 | 312 | 0.06 - 256 | 0.0 | 1.0 | 0.12 | 0.12 |
Tetracycline | 310 | 0.12 - 128 | 0.0 | 44.8 | 0.5 | 64 | 311 | 0.03 - 128 | 0.0 | 1.6 | 0.5 | 0.5 |
Levofloxacin | 284 | 0.5 - 2 | 0.0 | 0.0 | 1 | 2 | 305 | 0.25 - 8 | 0.3 | 0.3 | 1 | 1 |
Chloramphenicol | 285 | 0.5 - 4 | 0.0 | 1.1 | 4 | 4 | 307 | 0.5 - 4 | 0.0 | 0.0 | 4 | 4 |
Trimethoprim/Sulfamethoxazole | 284 | 0.12 - 8 | 5.6 | 1.8 | 0.25 | 0.5 | 305 | 0.25 - 8 | 24.3 | 18.0 | 0.25 | 4 |
MDR | 310 | 46.8 | 312 | 1.3 | ||||||||