Table 4 Microbial findings of unknown significance made by multiplex PCR but not by blood culture
From: Clinical evaluation of commercial nucleic acid amplification tests in patients with suspected sepsis
Patient | Multiplex PCR results | Clinical diagnosis |
|---|---|---|
1 | Acinetobacter baumannii | Acute pyelonephritis due to E. coli. |
2 | Acinetobacter baumannii | Infected chronic leg ulcer. A. baumannii not cultured from wound. |
3a | Acinetobacter baumannii, Stenotrophomonas maltophilia | Infected chronic leg ulcers. |
4 | Acinetobacter baumannii | Pulmonary embolism. |
5 | Candida krusei | Pneumonia verified by chest X-ray. |
6 | Candida parapsilosis | Acute pyelonephritis due to E. coli. |
7 | Enterobacter cloacae | Polycytemia vera. Fever and respiratory distress. Believed to have an adverse reaction to hydroxyurea. Infiltrate on chest X-ray. PCR from nasopharynx positive for human metapneumovirus and coronavirus. |
8 | Enterococcus faecalis | Acute pyelonephritis due to E. coli. |
9 | Enterococcus gallinarium | Nausea. No other diagnosis was made. |
10 | Escherichia coli | Acute otitis media. No other cultures were positive. |
11 | Klebsiella oxytoca | S. aureus endocarditis. |
12 | Klebsiella pneumoniae | Acute vomiting and fever. No other diagnosis was made. |
13 | Pseudomonas aeruginosa | Acute pyelonephritis due to E. coli. |
14a | Staphylococcus aureus, Streptococcus spp. | Influenza A verified by PCR. |
15 | Staphylococcus aureus | Pneumonia due to K. pneumoniae. Lymphoma. |
16 | Staphylococcus aureus | Pneumonia. Verified by chest X-ray. |
17 | Stenotrophomonas maltophilia | Pulmonary fibrosis and suspected pneumonia. |
18 | Streptococcus agalactiae | Arrived with severe sepsis. Diseased within 24 hours. |
19 | Streptococcus pneumoniae | Acute diabetic ketoacidosis. PCR from nasopharynx positive for human rhinovirus. Highly elevated neutrophil count. |
20 | Streptococcus pneumoniae | Acute pyelonephritis due to E. coli. |
21 | Streptococcus spp. | Goiter. |