Skip to main content

Table 3 Clinically relevant microbial findings made by multiplex PCR but not by blood culture

From: Clinical evaluation of commercial nucleic acid amplification tests in patients with suspected sepsis

Patient

Multiplex PCR results

Clinical diagnosis

1

Enterobacter aerogenes

Abdominal abscess.

2

Enterococcus faecalis a

Acute pyelonephritis. Grew E. faecalis in the urine.

3

Escherichia coli a

Acute pyelonephritis. Grew E. faecalis in the urine.

4

Escherichia coli a

Acute pyelonephritis. Grew E. faecalis in the urine.

5

Escherichia coli a

Acute pyelonephritis. Grew E. faecalis in the urine.

6

Escherichia coli

Acute cholecystitis. Elevated liver enzymes and positive computed tomography scan. Three months earlier, the patient had an acute cholecystitis with E. coli in blood cultures.

7

Escherichia coli

Acute pyelonephritis. Urine culture could not be obtained.

8

Escherichia coli

Abdominal abscess after appendectomy.

9

Klebsiella oxytoca

Perianal abscess.

10

Klebsiella pneumoniae

Acute pyelonephritis. Urine culture could not be obtained.

11

Staphylococcus aureus a

Infected leg ulcer. Grew S. aureus in the ulcer.

12

Stenotrophomonas maltophilia

Infected chronic leg ulcer.

13

Streptococcus pneumoniae

Clinical pneumonia, confirmed by chest x-ray.

14

Streptococcus pneumoniae

Fever, respiratory distress, pulmonary fibrosis. No other diagnosis was made. Chest x-ray inconclusive for pneumonia.

15

Streptococcus spp.

Acute cholangitis. Elevated liver enzymes and positive computed tomography scan.

  1. aConsidered as proven aetiology since the same species were found by culture from the site of infection.