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Table 2 Modeled CD4 gains after cART initiation for participants vaccinated before or after HIV diagnosis

From: Association between hepatitis B vaccine antibody response and CD4 reconstitution after initiation of combination antiretroviral therapy in HIV-infected persons

  Median [IQR] Change in CD4 Cell Count (cells/mm3) 1 Year After cART Initiation*
Characteristic Vaccinated before HIV diagnosis P value Vaccinated between HIV diagnosis and cART Initiation P value
CD4 <200 cells/mm3at cART initiation −208 [−283, −134] <0.001 −188 [−295, −81] <0.001
CD4 200–350 cells/mm3 at cART initiation −141 [−189, −94] <0.001 −81 [−167, 5] 0.067
HBV vaccine responder at cART initiation −18 [−79, 42] 0.551 26 [−55, 108] 0.528
  1. cART, combination antiretroviral therapy; IQR, interquartile range; HBV, hepatitis B virus; responder, antibody to HBV surface antigen ≥10 IU/L.
  2. *Model adjusted for HBV vaccine response status, race, gender, age at cART initiation, and AIDS before cART at baseline.