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Table 1 Risk factors associated with Candida spp infections in ICU

From: How to treat fungal infections in ICU patients

Candidaspecies Risk factors
C. albicans Prolonged ICU stay, Corticosteroids, prolonged antimicrobial use, chemotherapy, immunosuppressive agents, Diabetes mellitus, Advanced age, Central venous catheter, Gastrointestinal surgery, Total parenteral nutrition, Pancreatitis, Neutropenia, High disease severity score (APACHE II > 20), Renal replacement therapy, Malnutrition, Multiple site colonization, Major trauma, burns over 50% of body sites
C. glabrata Elderly, malignancies, total parenteral nutrition, central venous catheter, solid organ transplantation, antibiotics (piperacillin/tazobactam, vancomycin), exposure to fluconazole
C. parapsilosis Second most common isolated strain in children, central venous catheter or implanted devices, total parenteral nutrition
C. tropicalis Hematological patients, neutropenia
C. krusei Hematological malignancies, neutropenia, recent gastrointestinal surgery, use of piperacillin/tazobactam, vancomycin, prior exposure to fluconazole
C. guiillermondi Intravascular catheters