Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice

Table 2 Parasitemia status, survival time and percentage suppression of parasitemia in infected Swiss albino mice treated with khat extract in the 4 day suppressive test

Group	Antimalarial activities on day-4 p.i		Survival time (day)
Group	% Parasitemia (Mean ± SEM)	% suppression/ inhibition	Survival time (day)
Control	21.36 ± 1.32	0.00	8.3 ± 0.11
100 mg/kg	20.7 ± 0.87	3.09	10.8 ± 0.23*
500 mg/kg	19.7 ± 0.65	7.77	11.16 ± 0.68*
1000 mg/kg	19.3 ± 0.22	9.64	13.7 ± 0.52*
CQ (25 mg/kg)	0.00	100	30 ± 0.00

*showed significant difference at P < 0.001, (Kaplan Meier survival analysis, Mantel-Cox Log-rank test) from values of the control.

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