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Table 1 Hematological analysis of mice treated with khat followed by Pb A infection with reference to controls (n = 8)

From: Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice

Group

WBC*103/μL

RBC *106/ μL

Hb (g/dL)

HCT (%)

MCV (FL)

MCH (pg)

MCHC g/dL

Plt*103/ μL

Lym (%)

control (−ve)

3.8 ± 0.18

8.07 ± 0.3

12.72 ± 0.47

44.32 ± 1.67

54.85 ± 0.03

15.76 ± 0.05

28.72 ± 0.13

884.25 ± 32.5

87.2 ± 1.86

100 mg/kg§

3.52 ± 0.25

8.32 ± 0.29

12.75 ± 0.45

43.42 ± 2.06

52.06 ± 0.64

15.32 ± 0.02

29.46 ± 0.37

810 ± 45.7

80.32 ± 4.23

200 mg/kg§

2.85 ± 0.09**

8.7 ± 0.1

12.6 ± 0.18

45.1 ± 0.79

52.9 ± 0.55

15.67 ± 0.3

29.52 ± 0.53

766.7 ± 28.5

85.2 ± 1.72

300 mg/kg§

2.03 ± 0.49**

8.33 ± 0.15

11.66 ± 0.1*

43.02 ± 0.7

51.66 ± 0.58*

15.23 ± 0.2

29.42 ± 0.24

770 ± 17.15*

80.06 ± 2.17

Control (+ve)

6.64 ± 0.93

7.9 ± 1.02

14.14 ± 1.74

39.43 ± 5.55

47.8 ± 1.73

17.96 ± 0.9

37.34 ± 1.3

354 ± 68.73

74.92 ± 4.87

100 mg/kg + PbA§§

5.14 ± 1.71

6.9 ± 0.72

12.05 ± 1.23

34.47 ± 4.45

48.1 ± 0.89

17.5 ± 1.02

36.2 ± 0.71

328 ± 52

76.12 ± 11.15

200 mg/kg + PbA§§

4.57 ± 0.94

7.3 ± 0.34

13.18 ± 0.65

37.06 ± 1.62

50.5 ± 1.23

17.3 ± 1.1

34.5 ± 0.64

173 ± 37.02**

81.85 ± 7.67

300 mg/kg + PbA§§

4.09 ± 1.87*

7.1 ± 0.81

11.86 ± 1.48*

37.13 ± 4.43

50.1 ± 0.91

18.06 ± 0.93

36.1 ± 1.02

107 ± 21.66**

77.17 ± 8.09

  1. NB: Plt = platelet, Lym = lymphocyte, *showed significant difference (P < 0.05), **(P < 0.01). Significance level of uninfected but khat treated mice §were compared with –ve control group, while khat treated mice followed by PbA infection §§were compared to + ve control group.