TET reversed drug resistance in IEDR clinical isolates. (A) Chemical structure of TET. (B) A display of one strain showing that the drug resistance was reversed after TET treatment. Bacteria were incubated with 30 μg/ml TET for 24 hours before anti-tubercular drugs were added. (C) A statistical result of TET treatment. Two independent experiments were carried out and representative data were shown. **, p < 0.01.