Variable | Crude OR | Adjusted OR* | ||||||
---|---|---|---|---|---|---|---|---|
p-value | OR | 95% CI | p-value | OR | 95% CI | |||
Age-group at admission to service | ||||||||
< 1 year | 0.001 | 4.74 | 1.96 | 11.46 | 0.005 | 10.20 | 1.99 | 52.21 |
≥ 1 year | 1.00 | 1.00 | ||||||
ART initiated before 6 months of age | ||||||||
Yes | 0.027 | 2.86 | 1.12 | 7.25 | 0.860 | 0.86 | 0.16 | 4.63 |
No | 1.00 | 1.00 | ||||||
Use of ART >3 months | ||||||||
Yes | a | a | a | a | a | a | a | a |
No | 1.00 | |||||||
Advanced clinical and immunological disease (B3C123) | ||||||||
Yes | 0.003 | 4.41 | 1.68 | 11.61 | ||||
No | 1.00 | |||||||
Percentage CD4+ T-cell count | ||||||||
>25% | 1.00 | 1.00 | ||||||
15–24% | 0.296 | 1.87 | 0.58 | 6.07 | 0.244 | 2.62 | 0.52 | 13.22 |
<15% | 0.012 | 4.25 | 1.38 | 13.06 | 0.107 | 5.06 | 0.71 | 36.29 |
Baseline HIV viral load | ||||||||
≥ 100,000 | 0.004 | 6.42 | 1.84 | 22.36 | 0.115 | 3.31 | 0.75 | 14.71 |
<100,000 | 1.00 | 1.00 | ||||||
Origin of diagnosis | ||||||||
Mother had AIDS when she became pregnant | 1.00 | 1.00 | ||||||
Mother during prenatal care | a | a | a | a | a | a | a | a |
Mother during or following delivery, or father | 0.017 | 0.12 | 0.02 | 0.69 | 0.108 | 0.13 | 0.01 | 1.57 |
When the child became ill | 0.247 | 0.39 | 0.08 | 1.92 | 0.532 | 0.49 | 0.05 | 4.64 |
At diagnosis of a sibling | a | a | a | a | a | a | a | a |
Comorbidities | ||||||||
P. jiroveci pneumonia | 0.001 | 7.20 | 2.85 | 18.19 | 0.010 | 7.26 | 1.62 | 32.54 |
Thrombocytopenia | 0.001 | 5.02 | 1.89 | 13.33 | ||||
Severe recurrent bacterial infections | 0.003 | 4.27 | 1.61 | 11.32 | ||||
Candidiasis - any type | 0.005 | 3.47 | 1.45 | 8.30 | ||||
Chronic anemia | 0.012 | 6.73 | 1.53 | 29.64 | ||||
Hepatitis/ HIV | 0.004 | 3.85 | 1.53 | 9.65 | ||||
Wasting syndrome | 0.027 | 2.76 | 1.12 | 6.77 | ||||
Extrapulmonary cryptococcosis | 0.040 | 12.87 | 1.12 | 147.70 | ||||
Kidney disorders | 0.042 | 12.61 | 1.10 | 144.72 | 0.020 | 50.92 | 1.84 | 1411.87** |
Tuberculosis | 0.037 | 2.90 | 1.07 | 7.92 | ||||
Lymphadenopathy >0.5 cm at more than two sites | 0.061 | 0.44 | 0.19 | 1.04 | ||||
Severe recurrent bacterial infection | 0.082 | 2.51 | 0.89 | 7.05 | ||||
Prolonged diarrhea or gastroenteritis | 0.099 | 2.05 | 0.87 | 4.84 |