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Table 3 Factors predicting a sustained virologic response in HCV genotype 1-infected patients by univariate & multivariate analysis

From: Interleukin-28B gene non-TT allele strongly predicts treatment failure for genotype 1 infected chronic hepatitis C patients with advanced fibrosis: a case control study

Factors

Univariate

Multivariate

 

OR

95% CI

p-Value

OR

95% CI

p-Value

Age (years)

0.925

0.877–0.976

0.005

0.897

0.830–0.969

0.006

Male gender

3.694

1.819–6.912

0.002

4.813

1.512–15.324

0.008

Low viral load

2.6

1.154–5.858

0.021

   

RVR

7.233

2.84–18.422

<0.001

6.853

2.142–21.931

0.001

No advanced fibrosis (F1-3)

3.619

1.3–10.075

0.014

4.403

1.166–16.625

0.029

Fatty live

3.087

1.353–7.047

0.007

   

rs8099917 TT vs. non-TT

13.2

1.642–106.13

0.015

13.422

1.277–141.553

0.031

ALT (U/L)

1.005

1.000–1.011

0.049

   

Hemoglobin (mg/dL)

1.349

1.058–1.72

0.016

   

Platelet count (×10 3 /μL)

1.012

1.003–1.021

0.007

   
  1. HCV, hepatitis C virus; OR, Odds Ratio; CI, confidence interval; Low viral load, HCV RNA ≤800,000 IU/mL; RVR, rapid virologic response; ALT, alanine aminotransferase.