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Table 3 Factors predicting a sustained virologic response in HCV genotype 1-infected patients by univariate & multivariate analysis

From: Interleukin-28B gene non-TT allele strongly predicts treatment failure for genotype 1 infected chronic hepatitis C patients with advanced fibrosis: a case control study

Factors Univariate Multivariate
  OR 95% CI p-Value OR 95% CI p-Value
Age (years) 0.925 0.877–0.976 0.005 0.897 0.830–0.969 0.006
Male gender 3.694 1.819–6.912 0.002 4.813 1.512–15.324 0.008
Low viral load 2.6 1.154–5.858 0.021    
RVR 7.233 2.84–18.422 <0.001 6.853 2.142–21.931 0.001
No advanced fibrosis (F1-3) 3.619 1.3–10.075 0.014 4.403 1.166–16.625 0.029
Fatty live 3.087 1.353–7.047 0.007    
rs8099917 TT vs. non-TT 13.2 1.642–106.13 0.015 13.422 1.277–141.553 0.031
ALT (U/L) 1.005 1.000–1.011 0.049    
Hemoglobin (mg/dL) 1.349 1.058–1.72 0.016    
Platelet count (×10 3 /μL) 1.012 1.003–1.021 0.007    
  1. HCV, hepatitis C virus; OR, Odds Ratio; CI, confidence interval; Low viral load, HCV RNA ≤800,000 IU/mL; RVR, rapid virologic response; ALT, alanine aminotransferase.