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Table 2 Recommended immunizations against invasive pneumococcal disease using the 13-valent pneumococcal conjugate vaccine (PCV13) and the 23-valent pneumococcal polysaccharide vaccine (PPV23) for adults aged ≥19 years with functional or anatomic asplenia [17]

From: Recurrent severe invasive pneumococcal disease in an adult with previously unknown hyposplenia

Vaccination status PCV13 PPV23 Antibody measurement
Pneumococcal vaccine-naïve 1 dose of PCV13 1 dose of PPV23 ≥ 8 weeks after PCV13 Prior to revaccination with PPV23
Revaccination with PPV23 ≥ 5 years after last PPV23
Earlier vaccinated with PPV23 1 dose of PCV13 ≥ 1 year after last PPV23 Revaccination with PPV23 ≥ 8 weeks after PCV13 and ≥ 5 years after last PPV23 Prior to revaccination with PPV23