Table 3 Factors associated with fluctuation of HBV DNA greater than 0.5 log 10 IU/mL
Variables – N (%) | Patients with a change in viral load between two samples | p value | |
|---|---|---|---|
≤0.5 log10IU/mL (n = 32) | >0.5 log10IU/mL (n = 55) | ||
Gender (males) | 23 (72) | 40 (73) | 0.93 |
Age ≥ 30 yrs | 22 (69) | 26 (47) | 0.052 |
BMI < 21 (kg/m2) | 10 (31) | 32 (62) | 0.007 |
Platelets (giga/L)* | 188 [168–214] | 209 [161–247] | 0.94 |
∆ALT* | 3 [1-8] | 5 [3-9] | 0.19 |
∆AST* | 2 [1-6] | 4 [2-7] | 0.075 |
∆HBsAg* (n = 51) | 924 [355–1248] | 627 [218–1479] | 0.99 |
Genotype E (n = 63) | 15 (79) | 32 (73) | 0.60 |
Precore mutation C28 (n = 62) | |||
- Wild type | 9 (50) | 16 (36) | 0.32 |
- Mutation | 9 (50) | 28 (64) | |