BMC Infectious Diseases

Table 3 Analysis of changes in quality of life during the study period

From: Effects of long-term use of macrolides in patients with non-cystic fibrosis bronchiectasis: a meta-analysis of randomized controlled trials

Changes ^a of SGRQ	No. of studies	No. of patients		Effect size		Heterogeneity
Changes ^a of SGRQ	No. of studies	Macrolide	Control	WMD (95%CI)	P value	I ² (%)	P value
Total	5	213	204	−5.39(−9.88,-0.89)	0.02*	84	<0.001^b
Symptoms	3	146	142	−13.38(−30.62,3.86)	0.13	94	<0.001^b
Activity	2	87	84	−0.79(−4.67,3.09)	0.69	0	0.71
Impact	2	87	84	−5.88(−9.05,-2.71)	<0.001*	36	0.21

Abbreviations: WMD, weighted mean difference. ^achanges from baseline to the end of the study. ^bI² > 50%, a random-effects model was chosen; *It was suggestive of statistical significance.

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