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Table 2 Analysis of changes in lung function before and after treatment

From: Effects of long-term use of macrolides in patients with non-cystic fibrosis bronchiectasis: a meta-analysis of randomized controlled trials

Changes a

No. of studies

No. of patients

Effect size

Heterogeneity

Macrolide

Control

WMD (95%CI)

P value

I 2 (%)

P value

FEV1(L)

4

109

105

0.02(0–0.04)

0.02*

2

0.38

FEV1,% predicted

3

115

110

1.52(0.49-2.56)

0.004*

0

0.57

FVC(L)

3

98

95

0.05(−0.03-0.13)

0.25

54

0.11

  1. Abbreviations: WMD, weighted mean difference; 95%CI, 95% confidence interval; FEV1, forced expiratory volume in the first second; FVC, forced vital capacity. achange from baseline to the end of the study; * It was suggestive of statistical significance.
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BMC Infectious Diseases

ISSN: 1471-2334

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