Clonal dissemination of linezolid-resistant Staphylococcus capitis with G2603T mutation in domain V of the 23S rRNA and the cfr gene at a tertiary care hospital in China

Table 2 Clinical and resistant characteristics of clinical linezolid-resistant Staphylococcus capitis

Strain designation	Ward	Resource	Isolation(yy/mm/dd)	Linezolid usage (total dose/days)	MIC ( μg/mL)				cfr	Mutations in domain V of the 23S rRNA gene
Strain designation	Ward	Resource	Isolation(yy/mm/dd)	Linezolid usage (total dose/days)	LZD	VAN	Q/D	CLI	cfr	Mutations in domain V of the 23S rRNA gene
SA10106	ICU	catheter	2012/9/10	7.8 g/13 days	>256	1	>=8	2	+	G2603T
SA13096	IDD	blood	2012/9/13	–	>256	<=0.5	>=8	2	+	G2603T
SA23062	ICU	blood	2013/6/23	8.4 g/14 days	>256	1	>=8	2	+	G2603T
SA20062	ICU	blood	2013/7/20	13.2 g/22 days	>256	<=0.5	>=8	2	+	G2603T
SA11026	ICU	blood	2014/2/11	–	>256	<=0.5	>=8	2	+	G2603T

Note: ICU: intensive care unit; IDD: the department of infectious diseases; LZD: linezolid; VAN: vancomycin; Q/D: quinupristin/dalfopristin; CLI: clindamycin; −, no linezolid treatment.

ISSN: 1471-2334