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Table 2 Patient characteristics

From: Expression of inhibitory regulators of innate immunity in patients with active tuberculosis

 

Systemic host response

Local host response

 

Healthy controlsn = 29

Primary TBn = 54

All TB-positive bronchoscopy patientsn = 9

Demographics

   

Age (years)

31 (26–35)

28 (22–42)

35 (24–48)

Male sex (n, %)

21 (72%)

40 (74%)

7 (78%)

Smoker (n, %)

8 (28%)

27 (50%)

5 (56%)

HIV-positive (n, %)

0 (0%)

1 (2%)

1 (11%)

Symptoms

   

Fever (n, %)

0 (0%)

54 (100%)

9 (100%)

Night sweats (n, %)

0 (0%)

21 (39%)

1 (11%)

Weight loss (n, %)

0 (0%)

39 (72%)

4 (44%)

Fatigue (n, %)

1 (3%)

29 (54%)

4 (44%)

Shortness of breath (n, %)

0 (0%)

6 (11%)

0 (0%)

Productive cough (n, %)

2 (7%)

50 (93%)

8 (89%)

Signs

   

Temperature (°C)

36.9 (36.5-37.1)

37.4 (36.8-38.1)***

37.3 (36.5-38.3)*

MAP (mmHg)

83.3 (80–93.3)

80 (70–87)**

77 (73–82)**

Heart rate (bpm)

80 (78–84)

90 (81–100)***

84 (80–105)

Respiratory rate (brpm)

20 (20–24)

25 (24–28)***

20 (20–28)

BMI (w/l2)

24 (22.4-25.7)

17.7 (15.6-19.6)***

18.3 (16.3-22.6)**

  1. Abbreviations: TB tuberculosis, n number of patients, MAP mean arterial blood pressure, bpm beats per minute, brpm breaths per minute, BMI body mass index, expressed as weight (w) divided by length (l)2. Percentages given are within study groups. Data presented are medians with interquartile ranges. Mann Whitney-U test: *P < 0.05, **P < 0.01, ***P < 0.001 when compared to healthy controls.