Severe acute respiratory infection in children in a densely populated urban slum in Kenya, 2007–2011

BMC Infectious Diseases

Table 5 Incidence of select pathogens associated with SARI case status among children < 5, Kibera, Kenya

Pathogen	% SARI with pathogen detected (from Table3)	Pathogen specific-Number of SARI cases^a	Proportion of all clinic visits for SARI that went to study clinic	Adjusted No. of Pathogen specific-SARI cases^b	PAF^c	Final Adjusted Number of Cases^d	Rate/100PYO^e(95% CI)
Influenza A	11.2%	290	0.82	354	0.64	227	1.0 (0.4-1.7)
Influenza A and B combined	13.7%	355	0.82	433	0.64	277	1.3 (0.6-2.0)
Respiratory syncytial virus	20.7%	537	0.82	654	0.90	589	2.8 (2.4-3.2)
S. pneumoniae	1%	23	0.82	28	1.00	28	0.1 (0.1-0.2)
S. aureus	1.7%	41	0.82	51	1.00	51	0.2 (0.2-0.3)
Non-typhi Salmonella	1.6%	39	0.82	47	1.00	47	0.2 (0.2-0.3)
Salmonella Typhi	0.6%	18	0.82	22	1.00	22	0.1 (0.1-0.2)
Influenza B	2.6%	67	0.82	82	0.57	47	0.3 (0.0-0.5)
Adenovirus	29.5%	765	0.82	932	0.36	336	1.5 (0.1-2.9)
Parainfluenza virus 1	3.4%	88	0.82	107	0.77	83	0.4 (0.1-0.7)
Parainfluenza virus 3	9.4%	244	0.82	297	0.55	163	0.8 (0.2-1.4)
Any parainfluenza	15.0%	389	0.82	474	0.46	218	1.1 (0.2-1.9)
Human metapneumovirus	11.9%	308	0.82	376	0.53	199	0.9 (0.3-1.6)

^aPathogen-specific number of cases = % SARI (with swabs collected) with specific pathogen detected multiplied by 2,592—i.e. the number of overall SARI cases (with and without swabs collected).
^bAdjusted number of pathogen-specific SARI cases = Pathogen specific number of SARI cases/0.82 (Proportion of all clinic visits for SARI that were to study clinic).
^cPAF = Pathogen Attributable Fraction (see methods).
^dFinal adjusted number of cases = Adjusted No. of pathogen specific-SARI cases multiplied by PAF.
^eRates calculated per 100 person-years of observation.
March 1, 2007-February 28, 2011.

ISSN: 1471-2334