Table 2 Microbiological diagnosis
Definition 1 | Definition 2 | |||
|---|---|---|---|---|
Characteristic, n (%) | Early responders | Not-early responders | Early responders | Not-early responders |
n = 363 | n = 237 | n = 417 | n = 173 | |
Investigations or diagnostic test | ||||
Blood cultures | 231 (63.6) | 165 (69.6) | 270 (64.7) | 117 (67.6) |
Superficial swab and culture | 153 (42.1) | 131 (55.3) | 183 (43.9) | 96 (55.5) |
Needle aspiration | 31 (8.5) | 25 (10.5) | 36 (8.6) | 19 (11.0) |
Surgical sample | 38 (10.5) | 37 (15.6) | 48 (11.5) | 25 (14.5) |
Positive microbiological diagnosis | 161 (44.4) | 130 (54.9) | 193 (46.3) | 91 (52.6) |
Gram-positive cocci* | 130 (80.7) | 89 (68.5) | 156 (80.8) | 56 (61.5) |
Methicillin-sensitive Staphylococcus aureus | 54 (33.5) | 32 (24.6) | 61 (31.6) | 22 (24.2) |
Methicillin-resistant Staphylococcus aureus | 16 (9.9) | 17 (13.1) | 23 (11.9) | 8 (8.8) |
Coagulase-negative Staphylococcus | 24 (14.9) | 11 (8.5) | 27 (14.0) | 8 (8.8) |
Streptococcus pyogenes (group A β-haemolytic streptococci) | 10 (6.2) | 6 (4.6) | 13 (6.7) | 2 (2.2) |
Streptococcus agalactiae (group B β-haemolytic streptococci) | 4 (2.5) | 8 (6.2) | 7 (3.6) | 5 (5.5) |
Other β-haemolytic streptococci† | 13 (8.1) | 7 (5.4) | 14 (7.3) | 4 (4.4) |
Streptococcus pneumoniae | 1 (0.6) | 0 (0) | 1 (0.5) | 0 (0) |
Enterococcus faecalis | 11 (6.8) | 6 (4.6) | 12 (6.2) | 4 (4.4) |
Enterococcus faecium | 4 (2.5) | 3 (2.3) | 5 (2.6) | 2 (2.2) |
Other Gram-positive bacteria‡ | 4 (2.5) | 5 (3.8) | 4 (2.1) | 5 (5.5) |
Enterobacteriaceae§, other Gram-negative bacteria¶, other strict anaerobic bacteria** | 53 (32.9) | 46 (35.4) | 60 (31.1) | 37 (40.7) |
Non-fermenting Gram-negative bacilli†† | 16 (9.9) | 15 (11.5) | 20 (10.4) | 11 (12.1) |
Polymicrobial infections | 47 (29.2) | 29 (22.3) | 53 (27.5) | 19 (20.9) |
Yeasts | 2 (1.2) | 3 (2.3) | 2 (1.0) | 3 (3.3) |
Other microorganisms | 4 (2.5) | 1 (0.8) | 4 (2.1) | 1 (1.1) |
Bacteraemia | 20 (5.5) | 22 (9.3) | 27 (6.5) | 12 (6.9) |