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Table 4 Risk factors for TREATMENT DEFAULT among pulmonary tuberculosis patients from October 2009 to September 2010 (hierarchized model)

From: Effectiveness of RHZE-FDC (fixed-dose combination) compared to RH-FDC + Z for tuberculosis treatment in Brazil: a cohort study

Characteristics

%

OR

95% CI

adjOR

95% CI

FDC-RHZE

     

  No

66.4

1

 

1

 

  Yes

33.6

0.811

0.723 - 0.910

0.862

0.523 - 0.998

Age

     

  <38 years

54.4

1

 

1

 

  ≥38 years

45.5

0.620

0.555 - 0.692

0.599

0.484 - 0.742

Higher education occupation

     

  No

97.0

1

 

1

 

  Yes

3.0

0.355

0.217 - 0.582

0.223

0.081 - 0.610

Alcohol use

     

  No

81.8

1

 

1

 

  Yes

18.2

1.555

1.349 - 1.793

1.767

1.377 - 2.268

The unit offers DOT

    

  No

18.5

1

 

1

 

  Yes

81.5

0.946

0.826 - 1.082

0.979

0.850 - 1.128

The unit requests follow up smears

  

  No

21.7

1

 

1

 

  Yes

78.3

0.914

0.805 - 1.037

0.947

0.826 - 1.087

The unit has a laboratory facility

  

  No

65.2

1

 

1

 

  Yes

34.8

0.904

0.808 - 1.012

0.892

0.796 - 1.001

  1. Bold numbers are statistically significant findings. FDC = fixed-dose combination; R = rifampin; H = isoniazid; Z = pyrazinamide; E = ethambutol, DOT = directly observed treatment; OR = odds ratio; adjOR = adjusted odds ration; CI = confidence interval.