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Table 4 Risk factors for TREATMENT DEFAULT among pulmonary tuberculosis patients from October 2009 to September 2010 (hierarchized model)

From: Effectiveness of RHZE-FDC (fixed-dose combination) compared to RH-FDC + Z for tuberculosis treatment in Brazil: a cohort study

Characteristics % OR 95% CI adjOR 95% CI
FDC-RHZE      
  No 66.4 1   1  
  Yes 33.6 0.811 0.723 - 0.910 0.862 0.523 - 0.998
Age      
  <38 years 54.4 1   1  
  ≥38 years 45.5 0.620 0.555 - 0.692 0.599 0.484 - 0.742
Higher education occupation      
  No 97.0 1   1  
  Yes 3.0 0.355 0.217 - 0.582 0.223 0.081 - 0.610
Alcohol use      
  No 81.8 1   1  
  Yes 18.2 1.555 1.349 - 1.793 1.767 1.377 - 2.268
The unit offers DOT     
  No 18.5 1   1  
  Yes 81.5 0.946 0.826 - 1.082 0.979 0.850 - 1.128
The unit requests follow up smears   
  No 21.7 1   1  
  Yes 78.3 0.914 0.805 - 1.037 0.947 0.826 - 1.087
The unit has a laboratory facility   
  No 65.2 1   1  
  Yes 34.8 0.904 0.808 - 1.012 0.892 0.796 - 1.001
  1. Bold numbers are statistically significant findings. FDC = fixed-dose combination; R = rifampin; H = isoniazid; Z = pyrazinamide; E = ethambutol, DOT = directly observed treatment; OR = odds ratio; adjOR = adjusted odds ration; CI = confidence interval.