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Table 2 Characteristics of pulmonary tuberculosis patients according to the type of treatment from October 2009 to September 2010

From: Effectiveness of RHZE-FDC (fixed-dose combination) compared to RH-FDC + Z for tuberculosis treatment in Brazil: a cohort study

Characteristics FDC-RHZE RH-FDC + Z Total p-value
  N % N % N %  
Age        
  <38 years 1952 52.2 4100 55.6 6052 54.5 0.001
  ≥38 years 1785 47.8 3.274 44.4 5059 45.5  
  Total 3737   7374   11111   
Sex        
  Feminine 1301 34.8 2539 34.4 384 34.6 0.689
  Masculine 2436 65.2 4835 65.6 7271 65.4  
  Total 3737   7374   11111   
Illiteracy        
  No 3487 96.4 7035 97.4 10522 97.0 0.003
  Yes 132 3.7 189 2.6 321 3.0  
  Total 3619   7224   10843   
Higher education occupation        
  No 2773 97.0 5488 96.6 8261 96.7 0.384
  Yes 87 3.0 193 3.4 280 3.3  
  Total 286   5681   8541   
Living in prisons        
  No 3362 91.8 6320 87.9 9682 89.2 0.000
  Yes 302 8.2 869 12.1 1171 10.8  
  Total 3664   7189   10853   
Alcohol use        
  No 2835 81.8 5256 85.8 8091 84.3 0.000
  Yes 632 18.2 870 14.2 1502 15.7  
  Total 3467   6126   9593   
Diabetes        
  No 3174 92.4 5505 91.6 8679 91.9 0.174
  Yes 262 7.6 505 8.4 767 8.1  
  Total 3436   6010   9446   
Mental disorder        
  No 3363 97.8 5896 97.4 9259 97.5 0.194
  Yes 76 2.2 160 2.6 236 2.5  
  Total 3439   6056   9495   
Other co-morbidities        
  No 2640 81.3 4687 84.0 7327 83.0 0.001
  Yes 608 18.7 896 16.1 1504 17.0  
  Total 3248   5583   8831   
DOT        
  No 2746 75.9 5390 76.0 8136 75.9 0.954
  Yes 872 24.1 1706 24.0 2578 24.1  
  Total 3618   7096   10714   
HIV status        
  Negative 1267 74.7 2011 76.7 3278 75.9 0.135
  Positive 430 25.3 614 23.4 1044 24.1  
  Total 1697   2625   4322   
  1. FDC = fixed-dose combination; R = rifampin; H = isoniazid; Z = pyrazinamide; E = ethambutol, DOT = directly observed treatment.