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Table 2 Characteristics of pulmonary tuberculosis patients according to the type of treatment from October 2009 to September 2010

From: Effectiveness of RHZE-FDC (fixed-dose combination) compared to RH-FDC + Z for tuberculosis treatment in Brazil: a cohort study

Characteristics

FDC-RHZE

RH-FDC + Z

Total

p-value

 

N

%

N

%

N

%

 

Age

       

  <38 years

1952

52.2

4100

55.6

6052

54.5

0.001

  ≥38 years

1785

47.8

3.274

44.4

5059

45.5

 

  Total

3737

 

7374

 

11111

  

Sex

       

  Feminine

1301

34.8

2539

34.4

384

34.6

0.689

  Masculine

2436

65.2

4835

65.6

7271

65.4

 

  Total

3737

 

7374

 

11111

  

Illiteracy

       

  No

3487

96.4

7035

97.4

10522

97.0

0.003

  Yes

132

3.7

189

2.6

321

3.0

 

  Total

3619

 

7224

 

10843

  

Higher education occupation

       

  No

2773

97.0

5488

96.6

8261

96.7

0.384

  Yes

87

3.0

193

3.4

280

3.3

 

  Total

286

 

5681

 

8541

  

Living in prisons

       

  No

3362

91.8

6320

87.9

9682

89.2

0.000

  Yes

302

8.2

869

12.1

1171

10.8

 

  Total

3664

 

7189

 

10853

  

Alcohol use

       

  No

2835

81.8

5256

85.8

8091

84.3

0.000

  Yes

632

18.2

870

14.2

1502

15.7

 

  Total

3467

 

6126

 

9593

  

Diabetes

       

  No

3174

92.4

5505

91.6

8679

91.9

0.174

  Yes

262

7.6

505

8.4

767

8.1

 

  Total

3436

 

6010

 

9446

  

Mental disorder

       

  No

3363

97.8

5896

97.4

9259

97.5

0.194

  Yes

76

2.2

160

2.6

236

2.5

 

  Total

3439

 

6056

 

9495

  

Other co-morbidities

       

  No

2640

81.3

4687

84.0

7327

83.0

0.001

  Yes

608

18.7

896

16.1

1504

17.0

 

  Total

3248

 

5583

 

8831

  

DOT

       

  No

2746

75.9

5390

76.0

8136

75.9

0.954

  Yes

872

24.1

1706

24.0

2578

24.1

 

  Total

3618

 

7096

 

10714

  

HIV status

       

  Negative

1267

74.7

2011

76.7

3278

75.9

0.135

  Positive

430

25.3

614

23.4

1044

24.1

 

  Total

1697

 

2625

 

4322

  
  1. FDC = fixed-dose combination; R = rifampin; H = isoniazid; Z = pyrazinamide; E = ethambutol, DOT = directly observed treatment.