From: The epidemiology of herpes zoster and its complications in Medicare cancer patients
Patients | First events | Person-years of observation | IR Per 1,000 person-years (95% CI)1 | Adjusted IRR vs. non-cancer patients (95% CI)1 | P-value | |
---|---|---|---|---|---|---|
All Cancers | 1,027,609 | 66,222 | 4,161,133 | 15.9 (15.8-16.0) | 1.27 (1.25-1.29) | <0.001 |
Hematologic Cancers 2 | 82,832 | 7,574 | 244,187 | 31.0 (30.3-31.7) | 2.36 (2.30-2.42) | <0.001 |
Chronic Lymphocytic Leukemia | 14,035 | 1,754 | 56,875 | 30.8 (29.4-32.3) | 2.37 (2.26-2.49) | <0.001 |
Acute Lymphocytic or Acute Myeloid Leukemia | 9,614 | 257 | 7,125 | 35.9 (31.8-40.6) | 2.75 (2.43-3.11) | <0.001 |
Other Leukemia | 7,803 | 391 | 15,685 | 24.9 (22.5-27.5) | 1.90 (1.72-2.11) | <0.001 |
Hodgkin’s Lymphoma | 2,147 | 283 | 5,923 | 47.8 (42.5-53.7) | 3.56 (3.17-4.01) | <0.001 |
Non-Hodgkin’s Lymphoma | 49,233 | 4,891 | 158,773 | 30.7 (29.9-31.6) | 2.31 (2.24-2.39) | <0.001 |
Solid Cancers 2 | 944,777 | 58,670 | 3,921,307 | 14.9 (14.8-15.1) | 1.19 (1.17-1.21) | <0.001 |
Bladder Cancer | 67,811 | 4,140 | 293,432 | 14.1 (13.7-14.5) | 1.11 (1.08-1.16) | <0.001 |
Breast Cancer | 173,635 | 15,819 | 963,395 | 16.4 (16.2-16.7) | 1.17 (1.14-1.19) | <0.001 |
Colorectal Cancer | 129,761 | 7,354 | 504,238 | 14.6 (14.2-14.9) | 1.11 (1.08-1.14) | <0.001 |
Head and Neck Cancer | 48,876 | 2,530 | 173,559 | 14.6 (14.0-15.2) | 1.14 (1.09-1.19) | <0.001 |
Lung Cancer | 200,734 | 6,376 | 287,656 | 22.1 (21.6-22.7) | 1.61 (1.56-1.66) | <0.001 |
Melanoma | 52,026 | 3,961 | 268,256 | 14.8 (14.3-15.2) | 1.15 (1.11-1.19) | <0.001 |
Ovarian Cancer | 18,715 | 844 | 48,762 | 17.3 (16.2-18.5) | 1.21 (1.13-1.30) | <0.001 |
Prostate Cancer | 247,939 | 17,371 | 1,406,361 | 12.3 (12.2-12.5) | 1.12 (1.09-1.15) | <0.001 |
Soft Tissue Sarcoma | 5,280 | 275 | 18,206 | 15.1 (13.4-16.9) | 1.16 (1.03-1.31) | 0.016 |