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Table 2 Incidence of herpes zoster in cancer patients

From: The epidemiology of herpes zoster and its complications in Medicare cancer patients

 

Patients

First events

Person-years of observation

IR Per 1,000 person-years (95% CI)1

Adjusted IRR vs. non-cancer patients (95% CI)1

P-value

All Cancers

1,027,609

66,222

4,161,133

15.9 (15.8-16.0)

1.27 (1.25-1.29)

<0.001

Hematologic Cancers 2

82,832

7,574

244,187

31.0 (30.3-31.7)

2.36 (2.30-2.42)

<0.001

 Chronic Lymphocytic Leukemia

14,035

1,754

56,875

30.8 (29.4-32.3)

2.37 (2.26-2.49)

<0.001

 Acute Lymphocytic or Acute Myeloid Leukemia

9,614

257

7,125

35.9 (31.8-40.6)

2.75 (2.43-3.11)

<0.001

 Other Leukemia

7,803

391

15,685

24.9 (22.5-27.5)

1.90 (1.72-2.11)

<0.001

 Hodgkin’s Lymphoma

2,147

283

5,923

47.8 (42.5-53.7)

3.56 (3.17-4.01)

<0.001

 Non-Hodgkin’s Lymphoma

49,233

4,891

158,773

30.7 (29.9-31.6)

2.31 (2.24-2.39)

<0.001

Solid Cancers 2

944,777

58,670

3,921,307

14.9 (14.8-15.1)

1.19 (1.17-1.21)

<0.001

 Bladder Cancer

67,811

4,140

293,432

14.1 (13.7-14.5)

1.11 (1.08-1.16)

<0.001

 Breast Cancer

173,635

15,819

963,395

16.4 (16.2-16.7)

1.17 (1.14-1.19)

<0.001

 Colorectal Cancer

129,761

7,354

504,238

14.6 (14.2-14.9)

1.11 (1.08-1.14)

<0.001

 Head and Neck Cancer

48,876

2,530

173,559

14.6 (14.0-15.2)

1.14 (1.09-1.19)

<0.001

 Lung Cancer

200,734

6,376

287,656

22.1 (21.6-22.7)

1.61 (1.56-1.66)

<0.001

 Melanoma

52,026

3,961

268,256

14.8 (14.3-15.2)

1.15 (1.11-1.19)

<0.001

 Ovarian Cancer

18,715

844

48,762

17.3 (16.2-18.5)

1.21 (1.13-1.30)

<0.001

 Prostate Cancer

247,939

17,371

1,406,361

12.3 (12.2-12.5)

1.12 (1.09-1.15)

<0.001

 Soft Tissue Sarcoma

5,280

275

18,206

15.1 (13.4-16.9)

1.16 (1.03-1.31)

0.016

  1. Notes:
  2. 1IR = incidence rate; IRR = IR ratio; CI = confidence interval.
  3. 2P-value of difference in IR of HZ for hematologic vs. solid cancer <0.01.