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Table 1 Study population and input parameters (all costs are expressed in 2012 Euros)

From: Modelling the return on investment of preventively vaccinating healthcare workers against pertussis

 

Value

Source

Study population (n)

  

Fathers

20

*

Lactating mothers

13

*

Non-lactating mothers

7

*

Newborns

20

*

Parents per child

2

*

Average weight newborn (in kg)

2.2

[22]

Staff members

133

*

Medical consumption

  

Erythromycin cost per vial (solution of 20 mg)

€0.16

[16]

Erythromycin cost per tablet

€0.34

[16]

Azithromycin cost per tablet

€0.53

[16]

Laboratory investigation

  

Number of PCRs performed:

  

Children

20

*

Staff members

24

*

PCR costs per unit

€106.38

[18]

Number of serological tests performed:

  

Children

20 27

* *

Staff members

  

Serological test cost per unit

€48.96

[23]

Outbreak control management

  

Crisis meetings in the hospital

5

*

Duration of a crisis meeting (in minutes)

60

*

Personnel present at every crisis meeting:

  

Nurses

7

*

Neonatologists

1

*

Assistants

2

*

Amount of surgical masks used during the outbreak period

24

*

Costs per unit surgical mask

€1.22

[24]

Replacing sick staff members

  

Average working hours of nurses per week

32

[14]

Number of staff members not able to work for three days after performing the PCR test. Assumed they were all nurses

5

*

Number of hours of nurses absence due to the PCR test

68.57

Calculated

Number of staff members absent from the neonatology ward for one week. Assumed they were all nurses.

4

*

Number of hours of nurses absence due to illness (i.e. sick leave)

160

Calculated

Restrictions patient uptake

  

Regular occupation of the neonatology ward, patients per day

15

*

Average length of stay of neonates in neonatology ward (in days)

14

* & Personal communication

Average number of patients admitted on the neonatology ward per day

1,071

Calculated

Length of patient restriction uptake on the neonatology ward (in days)

10

*

Number of empty bed-days due to ward closure during the restriction period

58.93

Calculated

Cost per patient per day due to patient restriction

€798.18

[23]

Reduced workforce due to patient uptake restrictions

  

Average number of nurses & assistant working/day in the neonatology ward

30

*

Average number of consultant working/day in the neonatology ward

10

*

Average number of neonatologists working/day in the neonatology ward

6

*

Reduced working force due to ward closure:

  

On day 1

0%

Assumed

On day 2

5%

 

On day 3

10%

 

On day 4

15%

 

On day 5 and onwards

20%

 

Reduced working hours due to ward closure

  

Nurses

360

Calculated

Others

120

 

Neonatologists

0

 

Preventive vaccination

  

Infanrix IPV® costs

€34.50

[20]

Staff members vaccinated

133

*

Average number of new personal in neonatology ward /year (in %)

10

Assumed

Average number of new personnel in neonatology ward /year (absolute)

13.30

Calculated

Booster vaccination after years

8

[21]

Tariff personnel

  

The costs for the employer are higher than the tariffs paid to the employees, we therefore multiplied the costs per hour by

2.0

Assumed

Tariff per hour/nurses

€64.78

[15]

Tariff per hour/neonatologists

€155.04

[15]

Tariff per hour/others

€62.54

[15]

  1. *During the outbreak period, these data were collected by the occupational health service department of the AMC. In this paper we named this information the AMC database.