Skip to main content

Table 1 Baseline characteristics of the LTBI screening candidates

From: Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of Mycobacterium tuberculosis infection in HIV-infected patients: comparison with the tuberculin skin test and the QuantiFERON®-TB Gold In-tube

Demographics

Number (n = 48)

 Age; median [range]

38 [22–67]

 Gender

 

   Female

15 (31%)

   Male

33 (69%)

 Ethnic origin

 

   Sub Saharan

22 (46%)

   Caucasian

18 (38%)

   North African

3 (6%)

   Asian

3 (6%)

   South American

2 (4%)

Mtb exposure risk factors

 

 Presence of at least one major Mtb exposure risk factor

23 (48%)

   Born in high incidence countrya

22 (46%)

   Arrival in low incidence country ≤ 2 years

4 (8%)b

   Self-reported close contact with a case of TB

1

   Close contact with a case of sputum positive TB

1

 Otherc

5 (10%)

 Visitors of endemic countriesd

14 (29%)

LTBI reactivation risk factors

 

 Presence of ≥ 1 reactivation risk factor other than HIV

5 (10%)

   Diabetes

2 (4%)

   Body mass index < 18,5

2 (4%)

   Renal insufficiency +/− dialysis

1

   Solid tumor

1

   Alcoholism

1

Self-reported BCG vaccination status

 

 Vaccinated

16 (33%)

 Not vaccinated

17 (35%)

 Unknown

15 (31%)

HIV infection parameters

 

 HIV-1

47 (98%)

 HIV-2

1

 Seroconversion ≤ 2 years

9 (19%)e

 CD4+ T-cell count; median [range]

517 [1–1065]

 Viral load; median [range]

23242 [<40-1.107]f

  1. Units: Age (years); CD4+ T-cell count (cells/mm3); viral load (copies/ml).
  2. a>100 cases of TB/ 100000 inhabitants.
  3. bRepresents 17% of those born in a high incidence country.
  4. cProfessional risk, previous incarceration, asylum seeker, homeless.
  5. dConcerns the patients born in low incidence country.
  6. eDate of HIV seroconversion unknown for 40% of the enrolled subject.s
  7. fThe patient with an undetectable viral load is an elite controller (HIV-2 infected).