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Figure 1 | BMC Infectious Diseases

Figure 1

From: Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of Mycobacterium tuberculosis infection in HIV-infected patients: comparison with the tuberculin skin test and the QuantiFERON®-TB Gold In-tube

Figure 1

LTBI screening in treatment-naïve HIV-infected patients: relation between HBHA-IGRA, QFT-GIT and TST result. Forty-eight treatment naïve HIV-infected subjects underwent screening for latent tuberculosis with 3 different immunological tools: TST, QFT-GIT and HBHA-IGRA. HBHA-IGRA results were interpretable for 43 subjects. The test measures both IFN-γ responses to PPD and to HBHA that must be above or equal to 200 pg/ml and 50 pg/ml respectively for the assay to be considered positive. These cut-offs are represented in the graph as dotted lines. Each point on the graph represents the results of an individual. The format of the point (black square, black dot, white triangle or black and white square) represents the TST and QFT-GIT results obtained for the given individual, as indicated in the legend of the graph. As shown in the magnified square, 26 patients had undetectable IFN-γ levels in response to both PPD and HBHA, including 4 that had QFT-GIT positive tests.

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BMC Infectious Diseases

ISSN: 1471-2334

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