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Table 1 Analysis of intraspecific variability of rDNA ITS sequences for clinically important and emerging Candida species

From: Genetic diversity of medically important and emerging Candida species causing invasive infection

Candidaspecies Number of sequences Sequence length (base pair) Number of haplotypes Haplotype diversity* Number of variable sites (ITS1-5.8S-ITS2) Nucleotide diversity** (Pi)
Candida albicans 78 447 12 0.7802 9 0.00190
Candida dubliniensis 15 454 2 0.1333 6 0.00088
Candida glabrata 48 803 11 0.6179 20 0.00290
Candida tropicalis 41 437 9 0.7500 11 0.00182
Candida parapsilosis (sensu stricto) 35 430 2 0.2924 1 0.00068
Candida orthopsilosis 32 426 3 0.4456 7 0.00083
Candida metapsilosis 3 443 3 0.8333 8 0.00830
Meyerozyma guilliermondii*** 22 516 2 0.4848 1 0.00094
Pichia kudriavzevii*** 13 421 5 0.7821 4 0.00164
Clavispora lusitaniae*** 7 299 5 0.8571 17 0.02605
Candida intermedia 4 302 3 0.8333 18 0.02815
Wickerhamomyces anomalus*** 7 523 1 0 0 0
Candida haemulonii 3 286 1 0 0 0
  1. *The haplotype diversity is a measure of the presence of a single haplotype in a given species, considering the number of sequences analyzed and the total number of haplotypes found. This parameter varies from 0 to 1, with values of closer to 1 indicating higher variability.
  2. **The nucleotide diversity (Pi) is a measure of the average number of nucleotide differences per site between two sequences.
  3. ***Meyerozyma guilliermondii = teleomorph of Candida guilliermondii, Pichia kudriavzevii = teleomorph of Candida krusei, Clavispora lusitaniae = teleomorph of Candida lusitaniae, and Wickerhamomyces anomalus = teleomorph of Candida pelliculosa.