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Table 1 Analysis of intraspecific variability of rDNA ITS sequences for clinically important and emerging Candida species

From: Genetic diversity of medically important and emerging Candida species causing invasive infection

Candidaspecies

Number of sequences

Sequence length (base pair)

Number of haplotypes

Haplotype diversity*

Number of variable sites (ITS1-5.8S-ITS2)

Nucleotide diversity** (Pi)

Candida albicans

78

447

12

0.7802

9

0.00190

Candida dubliniensis

15

454

2

0.1333

6

0.00088

Candida glabrata

48

803

11

0.6179

20

0.00290

Candida tropicalis

41

437

9

0.7500

11

0.00182

Candida parapsilosis (sensu stricto)

35

430

2

0.2924

1

0.00068

Candida orthopsilosis

32

426

3

0.4456

7

0.00083

Candida metapsilosis

3

443

3

0.8333

8

0.00830

Meyerozyma guilliermondii***

22

516

2

0.4848

1

0.00094

Pichia kudriavzevii***

13

421

5

0.7821

4

0.00164

Clavispora lusitaniae***

7

299

5

0.8571

17

0.02605

Candida intermedia

4

302

3

0.8333

18

0.02815

Wickerhamomyces anomalus***

7

523

1

0

0

0

Candida haemulonii

3

286

1

0

0

0

  1. *The haplotype diversity is a measure of the presence of a single haplotype in a given species, considering the number of sequences analyzed and the total number of haplotypes found. This parameter varies from 0 to 1, with values of closer to 1 indicating higher variability.
  2. **The nucleotide diversity (Pi) is a measure of the average number of nucleotide differences per site between two sequences.
  3. ***Meyerozyma guilliermondii = teleomorph of Candida guilliermondii, Pichia kudriavzevii = teleomorph of Candida krusei, Clavispora lusitaniae = teleomorph of Candida lusitaniae, and Wickerhamomyces anomalus = teleomorph of Candida pelliculosa.