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Table 4 Haplotype frequencies of miR-146a C > G, miR-149 T > C, miR-196a2 T > C and miR-499 T > C SNPs in the Southern Han population

From: Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations

Haplotype Allele at marker Controls N (Freq) Patients N (Freq) Total N (Freq) OR (95% CI) Pvalue
miR-499 miR-196a2 miR-146a miR-149
1 T C C T 0.1639 0.1699 0.1643 1.00 ---
2 T T G T 0.1491 0.1689 0.1487 0.96 (0.51 - 1.79) 0.9
3 T T C T 0.1266 0.136 0.1378 0.67 (0.27 - 1.65) 0.38
4 T T C C 0.0662 0.1378 0.0953 2.33 (0.98 - 5.55) 0.057
5 T T G C 0.0761 0.0697 0.0828 0.60 (0.24 - 1.50) 0.27
6 T C G T 0.0926 0.0533 0.0796 0.35 (0.10 - 1.19) 0.092
7 T C G C 0.0711 0.0736 0.0652 0.95 (0.38 - 2.36) 0.91
8 T C C C 0.0607 0.0358 0.053 0.23 (0.05 - 0.96) 0.044
9 C T G T 0.0384 0.0174 0.0366 0.24 (0.04 - 1.37) 0.11
10 C C C T 0.0325 0.0065 0.0303 0.03 (0.01 - 0.63) 0.024
11 C T C T 0.0182 0.0365 0.0211 3.38 (0.54 - 21.22) 0.19
12 C C C C 0.0333 0.0188 0.0194 0.42 (0.04 - 4.04) 0.45
13 C C G C 0 0.0244 0.0189 0.00 (-Inf - Inf) 1
14 C T G C 0.0457 0 0.0181 0.00 (-Inf - Inf) 1
15 C T C C 0.0052 0.017 0.0158 1.41 (0.02 - 90.56) 0.87
16 C C G T 0.0203 0.0344 0.0131 1.35 (0.19 - 9.60) 0.76
Global haplotype association P-value: 0.0084
  1. Freq: frequency of haplotype, OR: odds ratio, N: number of subjects, CI: confidence interval.