Table 1 Characteristics of Uygur, Kazak and Southern Han populations for miR-146a C > G, miR-149 T > C, miR-196a2 T > C and miR-499 T > C SNPs detection
Characteristics | Uygur (n = 662) | Kazak (n = 613) | Southern Han (n = 654) |
|---|---|---|---|
Pulmonary TB patients | N = 301 | N = 251 | N = 354 |
Age, years range (mean ± SD) | 18-70 | 20-70 | 18-65 |
|  | (40.1 ± 14.7) | (37.5 ± 10.9) | (43.5 ± 12.0) |
Gender (female: male) | 144: 157 | 97:154 | 165:189 |
Body mass index (mean ± SD) | 20.7 ± 3.4 | 22.7 ± 3.9 | 26.3 ± 2.7 |
Sputum culture-proven | 148(49.2%) | 150(59.8%) | 169(47.9%) |
Chest X-ray and CT-proven | 156(51.8%) | 141(56.2%) | 176(49.6%) |
Pulmonary TB | 301(100%) | 251(100%) | 354(100%) |
Tuberculin skin test (>10 mm), no. (%) | 216(71.8%) | 199(79.3%) | 268(75.7%) |
TB history of relatives, no. (%) | 31(10.5%) | 36(14.6%) | 63(17.7%) |
BCG vaccination, no. (%) | 166(55.2%) | 125(49.8%) | 190(53.8%) |
Controls | N = 361 | N = 362 | N = 300 |
Age, years range (mean ± SD) | 20-65 | 20-72 | 19-64 |
|  | (37.0 ± 12.3) | (36.5 ± 9.6) | (46.1 ± 14.1) |
Gender (female: male) | 142: 219 | 149: 213 | 137:163 |
Body mass index (mean ± SD) | 23.0 ± 3.7 | 23.0 ± 3.9 | 24.6 ± 3.7 |
TB history of relatives, no. (%) | 23(6.4%) | 27(7.6%) | 17(5.7%) |
BCG vaccination, no. (%) | 164(45.3%) | 204(56.5%) | 162(53.9%) |