Table 2 Levels of T-cell populations in HIV exposed uninfected infants at 1 month of age according to maternal HIV RNA viral load at delivery
Cell population | HIV RNA ≥ 5 log10(n = 6) [median (IQR)] | HIV RNA < 5 log10(n = 57) [median (IQR)] | p-value* |
|---|---|---|---|
CD8 T-cells | |||
counts (cells/μl) | 1585 (1080–1702) | 1112 (71–1447) | 0.14 |
activated (%) | 25.8 (11.2-40.3) | 8.8 (3.3-18.3) | 0.09 |
naive (%) | 54.3 (42.8-67.8) | 79.8 (67.6-88.2) | 0.04 |
memory (%) | 54.6 (30.5-75.8) | 21.9 (14.3-40.3) | 0.014 |
CD4 T-cells | |||
counts (cells/μl) | 2594 (2174–3185) | 2291 (1955–3028) | 0.337 |
activated (%) | 5.3 (4.0-7.8) | 3.5 (2.1-6.5) | 0.557 |
naive (%) | 70.1 (60.4-74.8) | 70.3 (60.6-78.9) | 0.79 |
memory (%) | 19.8 (15.4-21.7) | 23.9 (13.2-45.8) | 0.574 |