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Table 2 Levels of T-cell populations in HIV exposed uninfected infants at 1 month of age according to maternal HIV RNA viral load at delivery

From: Impact of elevated maternal HIV viral load at delivery on T-cell populations in HIV exposed uninfected infants in Mozambique

Cell population HIV RNA ≥ 5 log10(n = 6) [median (IQR)] HIV RNA < 5 log10(n = 57) [median (IQR)] p-value*
CD8 T-cells    
counts (cells/μl) 1585 (1080–1702) 1112 (71–1447) 0.14
activated (%) 25.8 (11.2-40.3) 8.8 (3.3-18.3) 0.09
naive (%) 54.3 (42.8-67.8) 79.8 (67.6-88.2) 0.04
memory (%) 54.6 (30.5-75.8) 21.9 (14.3-40.3) 0.014
CD4 T-cells    
counts (cells/μl) 2594 (2174–3185) 2291 (1955–3028) 0.337
activated (%) 5.3 (4.0-7.8) 3.5 (2.1-6.5) 0.557
naive (%) 70.1 (60.4-74.8) 70.3 (60.6-78.9) 0.79
memory (%) 19.8 (15.4-21.7) 23.9 (13.2-45.8) 0.574
  1. Analysis is based on n = 63 infants with maternal HIV RNA measures available.
  2. *P-value from kruskal-wallis test.
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BMC Infectious Diseases

ISSN: 1471-2334

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