Table 4 Faecal concentrations of SMT19969 following single oral doses (Part 1)
Group | Dose | Mean (min – max) faecal concentrations (μg/g) | ||
|---|---|---|---|---|
Time post dose (hours) | ||||
0-24 | 24-48 | 48-72 | ||
C | 100 mg | 20 (<20 – 20) | 213 (<20 – 330) | 210 (<20 – 598) |
D | 400 mg | 239 (<20 – 317) | 1,132 (<20 – 3,340) | 677 (436 – 948) |
E TP1 | 1,000 mg | 1,194 (<20 – 2,310) | 855 (305 – 1,040) | 1,209 (183 – 1,970) |
F | 2,000 mg | <20 (<20 – <20) | 5713 (<20 – 11,800) | 6,478 (1,030 – 17,600) |