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Table 5 The frequencies of HLA-DRB1*15, HLA-DRB1*16, HLA-DRB1*03, HLA-DQB1*05, and HLA-DQB1*06 in 202 patients with B leprosy and 478 controls

From: Human leukocyte antigen class I and class II alleles are associated with susceptibility and resistance in borderline leprosy patients from Southeast Brazil

Haplotype Patients (N = 202) Controls (N = 478) p
  N AF n AF  
DRB1*15/DQB1*05 (#) 3 0.0148 3 0.0063 0.369
DRB1*15/DQB1*06 46 0.2277 82 0.1715 0.106
DRB1*16/DQB1*05 18 0.0891 21 0.0439 0.030
DRB1*16/DQB1*06 (#) 0 0.0000 2 0.0420 0.029
DRB1*03/DQB1*05 (#) 0 0.0000 0 0.0000 1.000
DRB1*03/DQB1*06 (#) 0 0.0000 1 0.0021 1,000
Total 67 0.3317 109 22.80 0.0055
Others alleles 135 0.6683 369 77.19  
  1. N: number of individuals, n: number of alleles (2n), AF: allele frequency, p: Fisher’s exact test (p ≤ 0.05), (#) haplotypes that are not in linkage disequilibrium, boldface: significant association.
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BMC Infectious Diseases

ISSN: 1471-2334

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