Human leukocyte antigen class I and class II alleles are associated with susceptibility and resistance in borderline leprosy patients from Southeast Brazil

Table 5 **The frequencies of HLA-DRB115, HLA-DRB116, HLA-DRB103, HLA-DQB105, and HLA-DQB1*06 in 202 patients with B leprosy and 478 controls**

Haplotype	Patients (N = 202)		Controls (N = 478)		p
	N	AF	n	AF
*DRB115/DQB105 (#)*	3	0.0148	3	0.0063	0.369
*DRB115/DQB106*	46	0.2277	82	0.1715	0.106
*DRB116/DQB105*	18	0.0891	21	0.0439	0.030
*DRB116/DQB106 (#)*	0	0.0000	2	0.0420	0.029
*DRB103/DQB105 (#)*	0	0.0000	0	0.0000	1.000
*DRB103/DQB106 (#)*	0	0.0000	1	0.0021	1,000
Total	67	0.3317	109	22.80	0.0055
Others alleles	135	0.6683	369	77.19

N: number of individuals, n: number of alleles (2n), AF: allele frequency, p: Fisher’s exact test (p ≤ 0.05), (#) haplotypes that are not in linkage disequilibrium, boldface: significant association.

ISSN: 1471-2334