|
BB
|
HLA allele
|
Patients (N = 88)
|
Controls (N = 478)
|
p
|
pc
|
OR
|
IC
|
|---|
| | |
N
|
%
|
n
|
%
| | | | |
|---|
| |
B*49
|
0
|
0.00
|
29
|
6.07
|
0.014
|
0.448
|
0.09
|
0.005–1.42
|
| |
B*58
|
10
|
11.36
|
24
|
5.03
|
0.028
|
0.896
|
2.42
|
1.11–5.27
|
| |
C*05
|
5
|
5.68
|
67
|
14.02
|
0.035
|
0.49
|
0.37
|
0.14–0.94
|
| |
C*12
|
19
|
21.59
|
64
|
13.39
|
0.050
|
0.70
|
1.78
|
1.00–3.15
|
|
BT
| |
Patients (N = 70)
|
Controls (N = 478)
| | | | |
| |
A*33
|
8
|
11.43
|
25
|
5.23
|
0.056
|
1.12
|
2.34
|
1.01–5.41
|
| |
B*40
|
2
|
2.86
|
50
|
10.46
|
0.047
|
1.50
|
0.25
|
0.06–1.06
|
| |
B*49
|
0
|
0.00
|
29
|
6.07
|
0.039
|
1.24
|
0.11
|
0.006–1.79
|
| |
B*53
|
6
|
8.57
|
14
|
2.93
|
0.031
|
0.992
|
3.11
|
1.15–8.37
|
| |
C*05
|
3
|
4.28
|
67
|
14.02
|
0.020
|
0.28
|
0.27
|
0.08–0.89
|
| |
C*16
|
9
|
12.86
|
26
|
5.44
|
0.031
|
0.434
|
2.56
|
1.15–5.73
|
| |
DRB1*03
|
20
|
28.57
|
85
|
17.78
|
0.049
|
0.637
|
1.85
|
1.05–3.27
|
|
BL
| |
Patients (N = 44)
|
Controls (N = 478)
| | | | |
| |
B*53
|
4
|
9.09
|
14
|
2.93
|
0.056
|
1.792
|
3.31
|
1.04–10.54
|
| |
DRB1*07
|
5
|
11.36
|
128
|
26.77
|
0.028
|
0.364
|
0.35
|
0.13–0.91
|
| |
DQB1*02
|
8
|
18.18
|
189
|
39.53
|
0.005
|
0.025
|
0.34
|
0.15–0.75
|
- N: number of individuals, n: number of alleles (2n), %: allele frequency, p: Fisher’s exact test (p ≤ 0.05), pc: corrected p value, OR: odds ratio, CI: confidence interval, boldface: significant association after Bonferroni´s correction.
