Human leukocyte antigen class I and class II alleles are associated with susceptibility and resistance in borderline leprosy patients from Southeast Brazil

Table 1 HLA alleles showing statistically significant differences in frequency between B leprosy patients and healthy controls

HLA allele	Patients (N = 202)		Controls (N = 478)		p	pc	OR	IC
	N	%	n	%
*B07**	38	18.81	61	12.78	0.043	1.37	1.58	1.02–2.50
*B49**	2	0.99	29	6.07	0.002	0.064	0.15	0.04–0.65
*B50**	4	1.98	30	6.28	0.019	0.608	0.30	0.10–0.87
*B53**	13	6.43	14	2.93	0.050	1.60	2.28	1.05–4.94
*C05**	12	5.94	67	14.02	0.002	0.032	0.38	0.20–0.73
*C16**	21	10.4	26	5.44	0.030	0.48	2.02	1.10–3.67
*DRB107**	33	16.34	128	26.77	0.003	0.039	0.53	0.30–0.80

N: number of individuals, n: number of alleles (2n), %: allele frequency, p: Fisher’s exact test (p ≤ 0.05), pc: corrected p value, OR: odds ratio, CI: confidence interval, boldface: significant association after Bonferroni´s correction.

ISSN: 1471-2334