Characteristic | Tested for tuberculosis n/N (%) | Unadjusted odds ratio (95% CI) | P value | Adjusted odds ratios (95% CI) | P value | |
---|---|---|---|---|---|---|
Age group (years) | 0-4 | 571/3291 (17) | Reference | Reference | ||
5-24 | 270 /587 (46) | 4.05 (3.4-4.9) | <0.001 | 3.3 (2.6-4.1) | <0.001 | |
25-44 | 1378/2473 (56) | 5.99 (5.3-6.8) | <0.001 | 3.5 (3.0-4.2) | <0.001 | |
45-64 | 611/1197 (51) | 4.96 (4.3-5.7) | <0.001 | 3.2 (2.7-3.8) | <0.001 | |
≥65 | 129/315 (39) | 3.30 (2.6-4.2) | <0.001 | 2.6 (2.0-3.4) | <0.001 | |
Sex | Female | 1664/4077 (41) | Reference | |||
Male | 1295/3786 (34) | 0.8 (0.7-0.8) | <0.001 | |||
Site | Chris Hani Baragwanath | 1618/4437 (36) | Reference | Reference | ||
Mapulaneng & Matikwana | 144/749 (19) | 0.4 (0.3-0.5) | <0.001 | 0.4 (0.3-0.5) | <0.001 | |
Edendale | 385/1156 (33) | 0.9 (0.8-0.99) | 0.046 | 0.7 (0.6-0.8) | <0.001 | |
Klerksdorp/Tshepong | 812/1521 (53) | 1.99 (1.8-2.2) | <0.001 | 1.1 (0.95-1.3) | 0.152 | |
Influenza | Negative | 2650/7098 (37) | Reference | |||
Positive | 309/765 (40) | 1.1 (0.9-1.3) | 0.097 | |||
HIV status | Negative | 862/3410 (25) | Reference | Reference | ||
Positive | 1877/3523 (53) | 3.4 (3.0-3.7) | <0.001 | 1.5 (1.3-1.7) | <0.001 | |
Underlying medical condition* | No | 2652/7041 (38) | Reference | |||
Yes | 307/821 (37) | 0.98 (0.85-1.14) | 0.879 | |||
Duration of symptoms prior to admission (days) | <7 | 1884/5957(32) | Reference | Reference | ||
≥7 | 1012/1765 (57) | 2.9 (2.6-3.2) | <0.001 | 1.3 (1.1-1.5) | 0.003 | |
Concurrent invasive bacterial infection** | No | 653/1832 (36) | Reference | |||
Yes | 24/46(52) | 1.96 (1.1- 3.5) | 0.023 | |||
Pneumococcal | No | 2435/6284 (39) | Reference | |||
Infection*** | Yes | 214/434 (49) | 1.5 (1.3-1.9) | <0.001 | ||
Receiving tuberculosis treatment at time of admission | No | 158/292 (54) | Reference | <0.001 | ||
Yes | 49/179 (27) | 0.3 (0.2-0.5) | ||||
Started on treatment for tuberculosis | No | 2301/6716 (34) | Reference | Reference | ||
Yes | 647/1108 (58) | 2.7 (2.4-3.1) | <0.001 | 1.2 (1.0-1.4) | 0.036 | |
Antibiotics prescribed | No | 77/332 (23) | Reference | Reference | ||
Yes | 2877/7515 (38) | 2.1 (1.6-2.7) | <0.001 | 1.9 (1.4-2.5) | <0.001 | |
Oxygen therapy | No | 1869/5145 (36) | Reference | |||
Yes | 1086/2698 (40) | 1.2 (1.1-1.3) | 0.001 | 1.2 (1.0-1.3) | 0.018 | |
ICU admission | No | 2936/7772 (38) | Reference | |||
Yes | 15/65 (23) | 0.5 (0.3-0.9) | 0.017 | |||
Duration of hospitalisation (days) | ≤7 | 1913/5666 (34) | Reference | Reference | ||
>7 | 1029/2143 (48) | 2.9 (2.6-3.2) | <0.001 | 1.2 (1.1-1.4) | 0.002 | |
Died | No | 2757/7321 (38) | Reference | Reference | ||
Yes | 195/509 (38) | 1.02 (0.9-1.2) | 0.769 |