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Table 1 Criteria for the phenotypes of multiple drug resistance in N. gonorrhoeae

From: Twenty-five-year changing pattern of gonococcal antimicrobial susceptibility in Shanghai: surveillance and its impact on treatment guidelines

Resistant phenotype PEN TET CIP CRO
CMRNG ≥2 ≥2 na na
PEN-TET ≥2 ≥2 na na
PEN-CIP ≥2 na ≥1 na
PEN-CRO ≥2 na na ≥0.125
TET-CIP na ≥2 ≥1 na
TET-CRO na ≥2 na ≥0.125
CIP-CRO na na ≥1 ≥0.125
PEN-TET-CIP ≥2 ≥2 ≥1 na
PEN-TET-CRO ≥2 ≥2 na ≥0.125
PEN-CIP-CRO ≥2 na ≥1 ≥0.125
TET-CIP-CRO na ≥2 ≥1 ≥0.125
PEN-TET-CIP-CRO ≥2 ≥2 ≥1 ≥0.125
  1. CMRNG: chromosomally-mediated resistant N. gonorrhoeae, non-penicillinase-producing N. gonorrhoeae (Non-PPNG) and tetracycline MIC <16 mg/L.
  2. PEN: penicillin; TET: tetracycline; CIP: ciprofloxacin; CRO: ceftriaxone (nonsusceptible); na: not applicable; MICs are presented as mg/L; Spectinomycin (SPT) was not listed.