Table 5 Haplotype analysis with different HCV outcomes
a) Haplotype analysis of rs1063478, rs2284191, and rs11244 in sequence | ||||
|---|---|---|---|---|
Haplotype | Uninfected N(%) | Infected N(%) | OR (95% CI) | P |
CGC | 461 (47.8) | 719 (49.6) | 1.00 | – |
TGC | 232 (24.1) | 290 (20.0) | 0.58 (0.47–0.73) | <0.001 |
CGT | 161 (16.7) | 241 (16.6) | 1.22 (0.94–1.58) | 0.125 |
TAC | 53 (5.5) | 76 (5.2) | 0.79 (0.53–1.17) | 0.232 |
CAC | 17 (1.8) | 74 (5.1) | 3.35 (1.87–5.99) | <0.001 |
Others* | 40 (4.1) | 50 (3.5) | 1.15 (0.71–1.87) | 0.572 |
b) Haplotype analysis of rs17587, rs2071543, rs2284191, rs7383287, rs376892, and rs416622 in sequence | ||||
Haplotype | Resolver N(%) | Chronic N(%) | OR (95% CI) | P |
GCGACG | 101 (26.2) | 213 (20.0) | 1.00 | – |
GCGGCG | 36 (9.3) | 18 (1.7) | 0.24 (0.13–0.45) | <0.001 |
ACGACG | 34 (8.8) | 26 (2.4) | 0.37 (0.21–0.65) | 0.001 |
GAGACG | 33 (8.5) | 73 (6.9) | 1.06 (0.66–1.71) | 0.818 |
GCGGTA | 24 (6.2) | 38 (3.6) | 2.37 (1.42–3.94) | 0.001 |
GCGATA | 13 (3.4) | 89 (8.4) | 3.31 (1.75–6.25) | <0.001 |
GAGGCG | 13 (3.4) | 59 (5.5) | 2.09 (1.09–4.02) | 0.027 |
Others* | 386 (34.2) | 566 (51.5) | 1.76 (1.28–2.41) | <0.001 |