Table 4 Interaction analysis between favorable SNPs and selected risk factors
a) Combined favorable alleles (rs1063478-T and rs2284191-G) and history of plasma donation | |||
|---|---|---|---|
Variables | Uninfected N(%) | Infected N(%) | OR (95% CI) |
0-2 favorable alleles with plasma donation | 184 (40.7) | 421 (58.1) | 1.00 |
3-4 favorable alleles with plasma donation | 154 (34.1) | 261 (36.0) | 0.66 (0.49-0.89) |
0-2 favorable alleles without plasma donation | 80 (17.7) | 18 (2.5) | 0.16 (0.08-0.30) |
3-4 favorable alleles without plasma donation | 64 (7.5) | 25 (3.4) | 0.18 (0.10-0.32) |
P for multiplicative interaction | P = 0.020 | ||
b) rs7383287 genotypes and history of blood donation | |||
Variables | Resolver N(%) | Chronic N(%) | OR (95% CI) |
AA genotypes with blood donation | 115 (59.6) | 349 (65.6) | 1.00 |
AG/GG genotypes with blood donation | 10 (5.2) | 42 (7.9) | 1.39 (0.64-2.99) |
AA genotypes without blood donation | 55 (28.5) | 127 (23.9) | 0.76 (0.51-1.13) |
AG/GG genotypes without blood donation | 13 (6.7) | 14 (2.6) | 0.34 (0.15-0.78) |
P for multiplicative interaction | P = 0.040 | ||