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Table 4 Clinical predictors of bacteraemia in non-febrile children in Guinea-Bissau

From: Prevalence of community-acquired bacteraemia in Guinea-Bissau: an observational study

Clinical parameter

 

Factor present (n)

 

Missing obs. 1

Bacteraemia

No bacteraemia

P-value

Sensitivity

Specificity

PPV 2

NPV 3

N = 21

N = 145

 

%

%

%

%

Tachycardia4

        

≥120 ≥ 160

-

21

145

N/A

100

0

13

N/A

≥130 ≥ 170

-

17

132

0.15

81

9

11

76

≥140 ≥ 180

-

10

76

0.68

48

48

12

86

Saturation5

1

1

3

0.42

5

98

25

88

Respiratory distress6

2

7

91

0.01

33

36

7

79

Anaemia7

-

2

18

1.00

10

87

10

88

Convulsions

5

1

0

0.13

5

100

100

88

Lung crepitation

-

6

55

0.41

29

62

10

86

Diarrhoea

-

10

55

0.40

48

62

15

89

Reduced consciousness8

10

1

3

0.43

5

98

25

88

Vomiting

-

7

46

0.88

33

68

13

88

MUAC9

        

<135 mm

-

5

36

1.00

28

72

12

88

<125 mm

-

2

15

1.00

11

88

12

88

<115 mm

-

0

5

1.00

0

96

0

87

Leukocyte count10

        

>11*109/L

44

8

39

0.41

50

63

17

89

>20*109/L

44

1

5

0.58

6

95

17

87

Malaria positive

23

1

1

0.24

6

99

50

88

  1. 1Missing observations may pertain either to the bacteraemic or the non-bacteraemic group.
  2. 2Positive predictive value.
  3. 3Negative predictive value.
  4. 4Heart rate cut off for tachycardia in children aged <1 year and 1–5 years, respectively.
  5. 5Oxygen saturation of haemoglobin <90%.
  6. 6Respiratory rate ≥40 per minute in children aged 1–5 years and ≥60 in children aged <1.
  7. 7Conjunctival pallor reported by the attending paediatrician.
  8. 8AVPU scale alertness level less than “awake”.
  9. 9Mid-upper arm circumference, measured on 149 children ≥6 months of age.
  10. 10Number of leukocytes per cubic millimeter.
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BMC Infectious Diseases

ISSN: 1471-2334

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