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Table 3 Rifampicin resistance detection by Xpert compared to phenotypic drug susceptibility testing

From: Diagnostic accuracy of the Xpert MTB/RIF assay for extrapulmonary and pulmonary tuberculosis when testing non-respiratory samples: a systematic review

Study

Xpert positive samples tested for drug resistance (n)

Rifampicin resistance detection

Prevalence of rif resistance by DST

Sensitivity

Specificity

TP

FP

FN

TN

Al-Ateah

17

2

0

0

15

11.7%

1.00

1.00

Hillemann

26

0

1

0

25

0%

Not estimable

0.96

Moure

63

0

0

0

63

0%

Not estimable

1.00

Vadwai

125

39

5

1

80

31.2%

0.98

0.94

Zmak

12

0

0

0

12

0%

Not estimable

1.00

Lawn*

16

1

2

0

13

6.3%

1.00

0.87

  1. *Comparison of urine Xpert MTB/RIF vs sputum phenotypic DST.