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Table 2 Cytokine production by splenocyte a cultures from immunized BALB/c mice

From: Alpha-galactosylceramide enhances protective immunity induced by DNA vaccine of the SAG5D gene of Toxoplasma gondii

Group

Cytokine production (pg/mL) b

IFN-γ

IL-4

IL-10

PBS

52.07 ± 8.23

36.36 ± 5.25

36 ± 4.98

pEGFP-C1

53.15 ± 8.71

39.24 ± 6.43

37.4 ± 6.33

α-GalCer

343.6 ± 50.88*

75.46 ± 5.7*

37.56 ± 3.66

pEGFP-C1-SAG5D

573.43 ± 60.2*

36.65 ± 3.52

40.77 ± 5.66

α-GalCer/pEGFP-C1-SAG5D

781.36 ± 57.57*#

76.73 ± 6.08*

41.33 ± 5.72

  1. aSplenocytes from 4 mice per group two weeks after the final immunization. bValues for IFN-γ at 96 hr, IL-4 at 24 hr, IL-10 at 72 hr are expressed as mean ± SD. *Compared with PBS or pEGFP-C1 group, P < 0.05; #compared with pEGFP-C1-SAG5D or α-GalCer, P < 0.05.
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BMC Infectious Diseases

ISSN: 1471-2334

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