| WHO anaemia severity classification at ART initiation | |||||
---|---|---|---|---|---|---|
All (n = 814) | None (29.5%; n = 240) | Mild (28.0%; n = 228) | Moderate(38.1%; n = 310) | Severe (4.4%; n = 36) | P-value | |
Age (at baseline), median (IQR) | 33 (29–39) | 34 (29–40) | 33 (29–40) | 32 (28–37) | 31 (27–37) | 0.008 |
Gender | Â | Â | Â | Â | Â | Â |
Male | 224 (27.5) | 102 (42.5) | 87 (38.2) | 30 (9.7) | 5 (13.9) | <0.001 |
Female | 590 (72.5) | 138 (57.5) | 141 (61.8) | 280 (90.3) | 31 (86.1) | Â |
WHO disease stage (at baseline) | Â | Â | Â | Â | Â | Â |
1 or 2 | 185 (22.7) | 56 (23.3) | 55 (24.1) | 69 (22.3) | 5 (13.9) | 0.584 |
3 or 4 | 629 (77.3) | 184 (76.7) | 173 (75.9) | 241 (77.7) | 31 (86.1) | Â |
Previous history of TB treatment | Â | Â | Â | Â | Â | Â |
No | 422 (51.8) | 109 (45.4) | 126 (55.3) | 162 (52.3) | 15 (69.4) | 0.023 |
Yes | 392 (48.2) | 131 (54.6) | 102 (44.7) | 148 (47.7) | 11 (30.6) | Â |
ART regimen | Â | Â | Â | Â | Â | |
AZT-free throughout | 646 (79.4) | 207 (86.3) | 187 (82.0) | 221 (71.3) | 31 (86.1) | <0.001 |
Any AZT exposure | 168 (20.6) | 33 (13.8) | 41 (18.0) | 89 (28.7) | 5 (13.9) | Â |
CD4 cell count (cells/μL)a a |  |  |  |  |  |  |
Median, IQR | 104 (50–156) | 113 (56–164) | 117 (63–169) | 93 (44–146) | 85 (31–125) | 0.002 |
<100 | 383 (47.2) | 109 (45.6) | 90 (39.7) | 164 (53.1) | 20 (55.6) | 0.013 |
≥100 | 428 (52.8) | 130 (54.4) | 137 (60.4) | 145 (46.9) | 16 (44.4) |  |
HIV viral load (log copies/mL), median (IQR) b | 4.8 (4.4-5.2) | 4.8 (4.3-5.1) | 4.8 (4.4-5.2) | 4.9 (4.5-5.3) | 5.0 (4.7-5.3) | 0.002 |
MCV (fL) c | Â | Â | Â | Â | Â | Â |
Median, IQR | 90 (86–95) | 92 (88–96) | 90 (87–94) | 89 (84–94) | 83 (75–95) | <0.001 |
<80 | 56 (7.0) | 5 (2.1) | 9 (4.0) | 28 (9.2) | 14 (38.9) | <0.001 |
80-100 | 671 (83.7) | 205 (87.0) | 200 (88.5) | 250 (82.2) | 16 (44.4) | Â |
>100 | 75 (9.4) | 26 (11.0) | 17 (7.5) | 26 (8.6) | 6 (16.7) | Â |
TB disease status | Â | Â | Â | Â | Â | Â |
TB free in first year of ART | 566 (69.5) | 180 (75.0) | 160 (70.2) | 204 (65.8) | 22 (61.1) | 0.148 |
Referred TB | 131 (16.1) | 34 (14.2) | 38 (16.7) | 54 (17.4) | 5 (13.9) | Â |
TB in first year of ART | 117 (14.4) | 26 (10.8) | 30 (13.2) | 52 (16.8) | 9 (25.0) | Â |