Table 1 Clinical features of the three confirmed H7N9 cases on admission

General information

  Age (years) and sex

49, Male

24, Female

43, Female

  Temperature (°C)*

40

39.5

36.8

37.0

Blood counts*

  White blood cells (×10⁹ per L)

1.8

6.1

7.6

4.0 ~ 10.0

  Lymphocytes (×10⁹ per L)

0.2

0.8

1.1

0.8 ~ 4.0

  Platelets (×10⁹ per L)

89

157

168

101 ~ 320

Serum biochemistry*

  Alanine aminotransferase (U/L)

76.8

24

40

8 ~ 40

  Aspartate aminotransferase (U/L)

63

40

35

8 ~ 40

  Lactate dehydrogenase (U/L)

435

188

110

109 ~ 245

  Creatine kinase (U/L)

324.5

66

50

20 ~ 140

  C-reactive protein (mg/L)

94

9.0

6

0 ~ 8

Arterial blood*

  PaCO₂ (mm Hg)

17

39

26

35.0 ~ 45.0 mmHg

  PaO₂ (mm Hg)

69

165

85

83 ~ 108 mmHg

  Blood oxygen saturation (%)

75

99

97

95 ~ 98%

Chest radiography

Bilateral lower-lobe infiltrate and left pleural effusion

Normal

Normal

Complication

ARDS and multi organ failure

No

No

Treatment

  Mechanical ventilation

Yes

No

No

  Antiviral treatment

Oseltamivir (75 mg Bid po) + Peramivir (600 mg Qd iv)

Oseltamivir (75 mg Bid po) + Peramivir (300 mg Qd iv)

Oseltamivir (75 mg Bid po) + Peramivir (300 mg Qd iv)

(Commenced 6 days after illness onset)

(Commenced 3 days after illness onset)

(Commenced 1 day after illness onset)

  Antibiotic treatment

Yes

Yes

Yes

  Oxygen treatment

Yes

Yes

Yes

Outcome

Died after 7 days of onset

Survived (mild case)

Survived (mild case)