Table 4 Case fatality, mortality rate and risk of death by month since starting TB treatment for retreatment TB episodes, by HIV status
From: Timing, rates, and causes of death in a large South African tuberculosis programme
HIV/ART status | Time on treatment 1 | n | Number of deaths | Cumulative case fatality (%) | Person months | Rate per 100Â pm (95% CI) | IRR (95% CI) | p-value for trend |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Â | 0.06 |
HIV negative or unknown | 1st month | 217 | 2 | 0.9 | 216 | 0.9 (0.2-3.7) | 1.0 | Â |
2nd month | 215 | 2 | 1.8 | 213 | 0.9 (0.2-3.7) | 1.01 (0.14-7.18) | Â | |
3rd-6th month | 213 | 4 | 3.7 | 844 | 0.5 (0.2-1.3) | 0.51 (0.09-2.79) | Â | |
7th-8th month | 209 | 0 | 3.7 | 418 | 0.0 | -- | Â | |
Overall | 217 | 8 | 3.7 | 1691 | 0.5 (0.2-0.9) | Â | Â | |
| Â | Â | Â | Â | Â | Â | Â | Â | <0.01 |
HIV positive on ART | 1st month | 277 | 14 | 5.1 | 270 | 5.2 (3.1-8.8) | 1.0 | Â |
2nd month | 263 | 7 | 7.6 | 259 | 2.7 (1.3-5.7) | 0.52 (0.21-1.29) | Â | |
3rd-6th month | 256 | 31 | 18.8 | 951 | 3.3 (2.3-4.6) | 0.63 (0.33-1.18) | Â | |
7th-8th month | 225 | 9 | 22.0 | 439 | 2.1 (1.1-3.9) | 0.39 (0.17-0.91) | Â | |
Overall | 277 | 61 | 22.0 | 1919 | 3.2 (2.5-4.1) | Â | Â | |
| Â | Â | Â | Â | Â | Â | Â | Â | 0.03 |
HIV positive not on ART | 1st month | 498 | 30 | 6.0 | 482 | 6.2 (4.4-8.9) | 1.0 | Â |
2nd month | 468 | 19 | 9.8 | 461 | 4.1 (2.6-6.5) | 0.66 (0.37-1.18) | Â | |
3rd-6th month | 449 | 66 | 23.1 | 1639 | 4.0 (3.2-5.1) | 0.65 (0.42-1.00) | Â | |
7th-8th month | 383 | 17 | 26.5 | 744 | 2.3 (1.4-3.7) | 0.37 (0.20-0.66) | Â | |
Overall | 498 | 132 | 26.5 | 3325 | 4.0 (3.3-4.7) | Â | Â |