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Table 3 Case fatality, mortality rate and risk of death by month since starting TB treatment for first TB episodes, by HIV status

From: Timing, rates, and causes of death in a large South African tuberculosis programme

HIV/ART status Time on treatment 1 n Number of deaths Cumulative case fatality (%) Person months Rate per 100 pm (95% CI) IRR (95% CI) p-value for trend
         <0.01
HIV negative or unknown 1st month 1124 10 0.9 1117 0.9 (0.5-1.7) 1.0  
2nd month 1114 8 1.6 1109 0.7 (0.4-1.4) 0.81 (0.32-2.04)  
3rd-6th month 1106 11 2.6 4401 0.2 (0.1-0.5) 0.28 (0.12-0.66)  
Overall 1124 29 2.6 6627 0.4 (0.3-0.7)   
         0.98
HIV positive on ART 1st month 375 15 4.0 367 4.1 (2.5-6.8) 1.0  
2nd month 360 2 4.5 358 0.6 (0.1-2.2) 0.14 (0.03-0.60)  
3rd-6th month 358 28 12.0 1372 2.0 (1.4-3.0) 0.50 (0.27-0.94)  
Overall 375 45 12.0 2097 2.1 (1.6-2.9)   
         0.22
HIV positive not on ART 1st month 1671 46 2.8 1647 2.8 (2.1-3.7) 1.0  
2nd month 1625 40 5.1 1604 2.5 (1.8-3.4) 0.89 (0.58-1.36)  
3rd-6th month 1585 148 14.0 6054 2.4 (2.1-2.9) 0.88 (0.63-1.22)  
Overall 1671 234 14.0 9306 2.5 (2.2-2.9)   
  1. 1Months 3–6 were grouped because mortality rates were observed to be stable in new TB episodes during this time period and the numbers of deaths were small.