Table 3 Case fatality, mortality rate and risk of death by month since starting TB treatment for first TB episodes, by HIV status
From: Timing, rates, and causes of death in a large South African tuberculosis programme
HIV/ART status | Time on treatment 1 | n | Number of deaths | Cumulative case fatality (%) | Person months | Rate per 100Â pm (95% CI) | IRR (95% CI) | p-value for trend |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Â | <0.01 |
HIV negative or unknown | 1st month | 1124 | 10 | 0.9 | 1117 | 0.9 (0.5-1.7) | 1.0 | Â |
2nd month | 1114 | 8 | 1.6 | 1109 | 0.7 (0.4-1.4) | 0.81 (0.32-2.04) | Â | |
3rd-6th month | 1106 | 11 | 2.6 | 4401 | 0.2 (0.1-0.5) | 0.28 (0.12-0.66) | Â | |
Overall | 1124 | 29 | 2.6 | 6627 | 0.4 (0.3-0.7) | Â | Â | |
| Â | Â | Â | Â | Â | Â | Â | Â | 0.98 |
HIV positive on ART | 1st month | 375 | 15 | 4.0 | 367 | 4.1 (2.5-6.8) | 1.0 | Â |
2nd month | 360 | 2 | 4.5 | 358 | 0.6 (0.1-2.2) | 0.14 (0.03-0.60) | Â | |
3rd-6th month | 358 | 28 | 12.0 | 1372 | 2.0 (1.4-3.0) | 0.50 (0.27-0.94) | Â | |
Overall | 375 | 45 | 12.0 | 2097 | 2.1 (1.6-2.9) | Â | Â | |
| Â | Â | Â | Â | Â | Â | Â | Â | 0.22 |
HIV positive not on ART | 1st month | 1671 | 46 | 2.8 | 1647 | 2.8 (2.1-3.7) | 1.0 | Â |
2nd month | 1625 | 40 | 5.1 | 1604 | 2.5 (1.8-3.4) | 0.89 (0.58-1.36) | Â | |
3rd-6th month | 1585 | 148 | 14.0 | 6054 | 2.4 (2.1-2.9) | 0.88 (0.63-1.22) | Â | |
Overall | 1671 | 234 | 14.0 | 9306 | 2.5 (2.2-2.9) | Â | Â |