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Table 1 Patient characteristics for 4,162 TB episodes occurring between 1995 and 2008

From: Timing, rates, and causes of death in a large South African tuberculosis programme

  

First episode n (%)

Retreatment episode n (%)

TOTAL

 

3170

992

Age at diagnosis

<35 years

438 (14)

86 (9)

35-44 years

1208 (38)

364 (37)

45-54 years

1261 (40)

470 (47)

>54 years

263 (8)

72 (7)

Treatment sequence

First episode

3170 (100)

 

Second episode

 

833 (84)

Third episode

 

140 (14)

Fourth or fifth episode

 

19 (2)

Time in employment at diagnosis

<1 year

237 (7)

27 (3)

1- < 5 years

526 (17)

116 (12)

5- < 10 years

461 (15)

149 (15)

10+ years

1946 (61)

700 (71)

Year diagnosed

1995-1998

509 (16)

234 (24)

1999-2002

848 (27)

330 (33)

2003-2005

908 (29)

290 (29)

2006-2008

905 (29)

138 (14)

HIV/ART status

Negative/unknown

1124 (36)

217 (22)

Positive: ART

375 (12)

277 (28)

Positive: no ART

1671 (53)

498 (50)

TB site

Pulmonary

1706 (54)

687 (69)

Extra-pulmonary1

1276 (40)

259 (26)

No data

188 (6)

46 (5)

Certainty of diagnosis2

Confirmed

740 (23)

269 (27)

Probable

760 (24)

314 (32)

Possible

856 (27)

264 (27)

No data

814 (26)

145 (15)

Outcome

Cured/Completed

2362 (75)

589 (59)

Failed

54 (2)

25 (3)

Did not complete

170 (5)

41 (4)

Transferred

276 (9)

136 (14)

Died

308 (10)

201 (20)

Autopsy data available

Alive

2862 (90)

791 (80)

Died – Cardiorespiratory autopsy

180 (6)

113 (11)

Died – No autopsy

128 (4)

88 (9)

  1. 1Extra-pulmonary cases were in the following sites: 59 lymph node, 489 pleural, 21 meningitis, 65 bone/joint, 124 other organs, 77 miliary.
  2. 2TB cases were classified as “confirmed” if at least one sputum culture was positive for Mycobacterium tuberculosis, “probable” if at least one sputum smear was positive for acid-fast bacilli, and “possible” if there was at least one negative sputum culture and/or sputum smear. The remaining cases lacked microbiological data and were treated as a separate “no data” category.