Table 1 Model parameter value and ranges

Discount rate (annual) (%)

0.03

Time horizon

Lifetime

Perspective

Societal

Smear positive cases

26

Culture positive cases

51

Detect-TB positive cases

41

Smear and culture positive cases

53

Smear and Detect-TB positive cases

48

Variable

Probability Value

Ambulatory TB prevalence

0.10

0.05

0.20

Hospitalization TB prevalence

0.30

0.25

0.35

Study TB prevalence

0.038

0.028

0.048

TB prevalence in RS (state in southern of Brazil)

0.047

0.037

0.057

SE smear

0.47

0.37

0.57

SE culture

0.93

0.83

0.99

SE Detect-TB

0.74

0.64

0.84

SE smear plus culture

0.96

0.86

0.99

SE smear plus Detect-TB

0.86

0.76

0.96