Twelve-month incidence and clearance of oral HPV infection in HIV-negative and HIV-infected men who have sex with men: the H2M cohort study

Table 4 Univariable and multivariable analyses of determinants of clearance ^a of 111 oral high-risk HPV infections in MSM using logistic regression analyses with generalized estimating equations (H2M study, Amsterdam 2010–2012)

	Univariable				Multivariable
	OR	(95% CI)	P -value ^b	aOR	(95% CI)	P -value ^b
HIV infection			0.049			0.167
No	1.0			1.0
Yes	0.4	(0.2 - 1.0)		0.5	(0.2 - 1.3)
Age (years) by category ^c			0.233			0.494
≤ 34	1.0			1.0
35 - 44	0.5	(0.1 - 2.6)		0.3	(0.1 - 2.0)
≥ 45	0.3	(0.1 - 1.6)		0.4	(0.1 - 2.3)
Current tobacco smoking ^d			0.696			0.910
No	1.0			1.0
Yes	0.9	(0.4 - 1.9)		1.1	(0.4 - 2.6)
Number of oral sex partners last 6 months by category			0.018			0.030
≤ 2	1.0			1.0
3 - 7	1.4	(0.5 - 3.9)		1.2	(0.4 - 3.6)
≥ 8	3.6	(1.4 - 9.0)		3.4	(1.3 - 9.0)

Abbreviations: MSM men who have sex with men, OR odds ratio, aOR adjusted odds ratio, CI confidence interval.
^aClearance was defined as two consecutive negative results after a positive test result at baseline (1-0-0).
^bBased on Wald test. Significant P values are in bold.
^cAs collected at baseline. All other variables were based on data collected at the 6-month follow-up visit.
^dIn case of missing values at the 6-month follow-up visit, baseline smoking status was used.

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