Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study

BMC Infectious Diseases

Table 4 Characteristics and outcomes of adult patients hospitalized with acute respiratory symptoms and diagnosed with RSV as reported in published studies

Study	This study (all adults)	Lee 2013 (all adults)	Widmer, 2012 (50+ yrs)	Falsey, 2005 (65+ yrs)	Dowell, 1996 (all adults)	Falsey, 1995 (65+ yrs)	Vikerfors, 1987 (all adults)
Age	Median 74 yrs IQR 62-85	Median 80 yrs IQR 68-86	Median 68 yrs IQR 56-78	Mean 76 yrs SD 13	Mean 61 yrs range 21-89	Mean 80 yrs SD 8	Median 75 yrs
Underlying illness
Any	97%	87%	-	-	-	-	56%
Lung disease	36%	36%	68%	54%	>65%*	43%	14%
Cardiac disease	52%	-	48%	58%	>49%*	63%	-
Immunosuppressed	31%	14%	61%		-	-	-
Complications
LRT complication	52%	72%	-	-	-	63%‡	-
Pneumonia†	30%	42%	-	31%	40%	48%	-
Cardiovascular	22%	14%	-	13% (CHF)	-	20% (CHF)‡	-
Co-pathogen identified	13%	13%	0	15% sputum	14%	17% sputum	25%
Co-pathogen identified	13%	13%	0	3% blood		4% blood	25%
Hospital course
Required ICU	15%	-	10%	15%	21%	18%	-
Required MV	9%	2%	3%	13%	7%	10%	-
Length of stay	Median 6d	Median 7d	Median 3d	Mean 14d	Mean 9d	Mean 16d	-
Case fatality rate	6% (in hospital)	9% (30d)	7% (in hospital)	8% (not specified)	-	10% (in hospital)	0

*65% of patients had COPD, 44% had asthma; 49% had coronary artery disease; 37% congestive heart failure.
†Confirmed by CXR, or pulmonary infiltrates present on CXR.
‡Derived from principal discharge diagnoses.
Abbreviations: LRT = lower respiratory tract, ICU = intensive care unit, MV = mechanical ventilation.

ISSN: 1471-2334