Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study

BMC Infectious Diseases

Table 3 Published studies of adult patients hospitalized with acute respiratory symptoms and RSV infection

Reference	Years of study	Type of study	Geographic location	Population	Means of diagnosis
Lee [25]	2009-2011	Retrospective cohort	Hong Kong, China	607 adults (≥ 18 years) with acute respiratory infection	Immunofluorescence assay, nasopharyngeal aspirates
Widmer [21]	2006-2009	Prospective cohort	Tennessee, USA	31 adults ≥ 50 years with respiratory symptoms or non-localizing fever	RT-PCR, frozen nasal and throat swabs
Falsey [9]	1999-2003	Prospective cohort	New York, USA	132 adults ≥ 65 years with underlying cardiopulmonary disease and acute respiratory symptoms	Culture and RT-PCR of nasopharyngeal specimens; and acute and convalescent serology
Dowell [28]	1990-1992	Prospective cohort	Ohio, USA	47 community dwelling adults (≥ 18 years) with pneumonia	Acute and convalescent serology
Falsey [20]	1989-1992	Prospective cohort	New York, USA	145 community dwelling adults ≥ 65 years with acute cardiopulmonary conditions or influenza-like illness	Antigen detection, culture on nasopharyngeal specimens; acute and convalescent serology
Vikerfors [30]	1971-1980	Retrospective cohort	Orebro, Sweden	57 adults (> 16 years) with pneumonia	Immunofluorescence assay on nasopharyngeal secretions; acute and convalescent serology

Abbreviations: RT-PCR, reverse transcriptase PCR; USA, United States of America.

ISSN: 1471-2334