Figure 4From: Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A Serum IDO activity is negatively correlated with the 85A peptide specific IFN-γ ELISPOT response. IDO activity at baseline for both UK and South African volunteers was correlated with the 85A peptide specific IFN-γ ELISPOT response at A) week 4 and B) week 24 following vaccination with MVA85A (Spearman’s correlation P < .05).Back to article page